AR-R17779 HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530349

CAS#: 178419-42-6 (HCl)

Description: AR-R17779 is a selective alpha7 nicotinic agonist (Ki values are 190 and 16000 nM for rat α7 and α4β2 receptors respectively). AR-R17779 improves learning and memory in rats. Treatment with AR-R17779 significantly reduced atherosclerotic plaque area and improved survival of mice. Treatment with AR-R17779 also suppressed abdominal aortic aneurysm formation. Quantitative RT-PCR of the aorta revealed that mRNA expression levels of interleukin-1β, interleukin-6 and NOX2 were significantly decreased in AR-R17779-treated mice compared with Ang II+HFD mice. AR-R17779 treatment also reduced blood pressure and serum lipid levels.

Price and Availability

Size Price Shipping out time Quantity
200mg USD 2650 2 Weeks
500mg USD 3650 2 Weeks
1g USD 4750 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-26. Prices are subject to change without notice.

AR-R17779 hydrochloride, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530349
Name: AR-R17779 HCl
CAS#: 178419-42-6 (HCl)
Chemical Formula: C9H15ClN2O2
Exact Mass:
Molecular Weight: 218.681
Elemental Analysis: C, 49.43; H, 6.91; Cl, 16.21; N, 12.81; O, 14.63

Related CAS #: 178419-42-6 (HCl)   178419-47-1 (free base)    

Synonym: AR-R17779 hydrochloride; AR-R17779; AR-R-17779; AR-R 17779.

IUPAC/Chemical Name: (3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidine]-2'-one hydrochloride


InChi Code: InChI=1S/C9H14N2O2.ClH/c12-8-10-5-9(13-8)6-11-3-1-7(9)2-4-11;/h7H,1-6H2,(H,10,12);1H/t9-;/m0./s1

SMILES Code: O=C(NC1)O[C@@]21CN3CCC2CC3.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Related CAS#
CAS#178419-42-6 (AR-R17779 hydrochloride)
CAS#178419-47-1 (AR-R17779 free base)


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