NSC61610

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530323

CAS#: 500538-94-3

Description: NSC61610 is a LANCL2 ligand. NSC61610 showed anti-inflammatory activity and potential useful for inflammatory bowel disease and influenza-driven inflammation . LANCL2 is a novel therapeutic target for the discovery and development of new classes of orally active drugs against chronic metabolic, immune-mediated and infectious diseases.

Chemical Structure

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NSC61610
CAS# 500538-94-3
Instruction

Theoretical Analysis

MedKoo Cat#: 530323
Name: NSC61610
CAS#: 500538-94-3
Chemical Formula: C34H24N6O2
Exact Mass: 548.20
Molecular Weight: 548.606
Elemental Analysis: C, 74.44; H, 4.41; N, 15.32; O, 5.83

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: NSC61610; NSC-61610; NSC 61610; MLS000766212; SMR000528839.

IUPAC/Chemical Name: N1,N4-bis(3-(1H-benzo[d]imidazol-2-yl)phenyl)terephthalamide

InChi Key: WSXIJTIFOWCMIQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C34H24N6O2/c41-33(35-25-9-5-7-23(19-25)31-37-27-11-1-2-12-28(27)38-31)21-15-17-22(18-16-21)34(42)36-26-10-6-8-24(20-26)32-39-29-13-3-4-14-30(29)40-32/h1-20H,(H,35,41)(H,36,42)(H,37,38)(H,39,40)

SMILES Code: C1=CC=C2C(=C1)NC(=N2)C3=CC(=CC=C3)NC(=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC(=C5)C6=NC7=CC=CC=C7N6

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 548.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zhang Q, He Q, Xue F, Ma J. Inhibitor screening of lactate dehydrogenase C4
from black-lipped pika in the Western Sichuan Plateau. Biosci Biotechnol Biochem.
2014;78(4):651-4. doi: 10.1080/09168451.2014.890038. PubMed PMID: 25036963.


2: Lu P, Hontecillas R, Philipson CW, Bassaganya-Riera J. Lanthionine synthetase
component C-like protein 2: a new drug target for inflammatory diseases and
diabetes. Curr Drug Targets. 2014 Jun;15(6):565-72. Review. PubMed PMID:
24628287.


3: Lu P, Hontecillas R, Horne WT, Carbo A, Viladomiu M, Pedragosa M, Bevan DR,
Lewis SN, Bassaganya-Riera J. Computational modeling-based discovery of novel
classes of anti-inflammatory drugs that target lanthionine synthetase C-like
protein 2. PLoS One. 2012;7(4):e34643. doi: 10.1371/journal.pone.0034643. PubMed
PMID: 22509338; PubMed Central PMCID: PMC3324509.