T-2000

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526946

CAS#: 97846-21-4

Description: T-2000, also known as DMMDPB, is a GABA receptor agonist potentially for the treatment of essential tremor.


Price and Availability

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Price

Size
Price

Size
Price

T-2000 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 526946
Name: T-2000
CAS#: 97846-21-4
Chemical Formula: C20H20N2O5
Exact Mass: 368.1372
Molecular Weight: 368.389
Elemental Analysis: C, 65.21; H, 5.47; N, 7.60; O, 21.71


Synonym: T-2000, T 2000, T2000, DMMDPB

IUPAC/Chemical Name: 1,3-Dimethoxymethyl-5,5-diphenylbarbituric acid

InChi Key: RRFBTKHQZRCRSS-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H20N2O5/c1-26-13-21-17(23)20(15-9-5-3-6-10-15,16-11-7-4-8-12-16)18(24)22(14-27-2)19(21)25/h3-12H,13-14H2,1-2H3

SMILES Code: O=C(N(COC)C(C1(C2=CC=CC=C2)C3=CC=CC=C3)=O)N(COC)C1=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Hadj Tahar A, Chuang R, Steeves T, Jog M, Lang A, Grimes D. Efficacy and safety of T2000 in older patients with essential tremor. Parkinsonism Relat Disord. 2013 Apr;19(4):485-6. doi: 10.1016/j.parkreldis.2012.11.014. PubMed PMID: 23254160.

2: Melmed C, Moros D, Rutman H. Treatment of essential tremor with the barbiturate T2000 (1,3-dimethoxymethyl-5,5-diphenyl-barbituric acid). Mov Disord. 2007 Apr 15;22(5):723-7. PubMed PMID: 17265458.