WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 328048
Description: Saripidem, also known as SL-85.0274; SL-850274, is a GABA receptor agonist potentially for the treatment of anxiety.
MedKoo Cat#: 328048
Chemical Formula: C19H20ClN3O
Exact Mass: 341.1295
Molecular Weight: 341.839
Elemental Analysis: C, 66.76; H, 5.90; Cl, 10.37; N, 12.29; O, 4.68
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Saripidem; SL-85.0274; SL-850274; SL85.0274; SL850274.
IUPAC/Chemical Name: N-((2-(p-Chlorophenyl)-imidazo(1,2-a)pyridin-3-yl)methyl)-N-methylbutyramide.
InChi Key: LIFDPEORUVTOCP-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H20ClN3O/c1-3-6-18(24)22(2)13-16-19(14-8-10-15(20)11-9-14)21-17-7-4-5-12-23(16)17/h4-5,7-12H,3,6,13H2,1-2H3
SMILES Code: CCCC(N(CC1=C(C2=CC=C(Cl)C=C2)N=C3C=CC=CN31)C)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 341.839 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Anilkumar NC, Sundaram MS, Mohan CD, Rangappa S, Bulusu KC, Fuchs JE, Girish
KS, Bender A, Basappa, Rangappa KS. A One Pot Synthesis of Novel Bioactive
Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase
A2. PLoS One. 2015 Jul 21;10(7):e0131896. doi: 10.1371/journal.pone.0131896.
PubMed PMID: 26196520; PubMed Central PMCID: PMC4511007.
2: Sanger DJ. Behavioural effects of novel benzodiazepine (omega) receptor
agonists and partial agonists: increases in punished responding and antagonism of
the pentylenetetrazole cue. Behav Pharmacol. 1995 Mar;6(2):116-126. PubMed PMID: