WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526895

CAS#: 1222800-79-4

Description: ML-324, also known as CID-44143209, is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.ML-324 displays submicromolar inhibitory activity toward JMJD2E (in vitro) and possesses excellent in vitro ADME properties. ML324 displays excellent cell permeability providing an opportunity for more extensive cell-based studies of JMJD2 enzymes to be undertaken. In addition, ML324 demonstrates potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 450 2 Weeks
200mg USD 750 2 Weeks
500mg USD 1450 2 Weeks
1g USD 2150 2 Weeks
2g USD 3450 2 Weeks
5g USD 5850 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-27. Prices are subject to change without notice.

ML-324, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 526895
Name: ML-324
CAS#: 1222800-79-4
Chemical Formula: C21H23N3O2
Exact Mass: 349.179
Molecular Weight: 349.434
Elemental Analysis: C, 72.18; H, 6.63; N, 12.03; O, 9.16

Synonym: ML-324; ML 324; ML324; CID-44143209; CID 44143209; CID44143209.

IUPAC/Chemical Name: N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-benzamide


InChi Code: InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Pathak SS, Maitra S, Chakravarty S, Kumar A. Histone Lysine Demethylases of
JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in
the Etiopathology of Depression. Neuropsychopharmacology. 2016 Oct 6. doi:
10.1038/npp.2016.231. PubMed PMID: 27711046.

2: Rai G, Kawamura A, Tumber A, Liang Y, Vogel JL, Arbuckle JH, Rose NR,
Dexheimer TS, Foley TL, King ON, Quinn A, Mott BT, Schofield CJ, Oppermann U,
Jadhav A, Simeonov A, Kristie TM, Maloney DJ. Discovery of ML324, a JMJD2
demethylase inhibitor with demonstrated antiviral activity. 2012 Dec 17 [updated
2013 Sep 16]. Probe Reports from the NIH Molecular Libraries Program [Internet].
Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Available from
PubMed PMID: 24260783.