Eberconazole Nitrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 329004

CAS#: 130104-32-4 (nitrate)

Description: Eberconazole Nitrate, also known as Ebernet, is an azole antifungal agent and broad-spectrum imidazole derivative. Eberconazole Nitrate is effective in dermatophytoses, candidiasis, and pityriasis treatment.

Price and Availability


USD 3250

USD 4850

USD 6250

Eberconazole Nitrate is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 1 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 329004
Name: Eberconazole Nitrate
CAS#: 130104-32-4 (nitrate)
Chemical Formula: C18H15Cl2N3O3
Exact Mass:
Molecular Weight: 392.236
Elemental Analysis: C, 55.12; H, 3.85; Cl, 18.08; N, 10.71; O, 12.24

Related CAS #: 130104-32-4 (nitrate)   128326-82-9 (free base)    

Synonym: Eberconazole Nitrate; Ebernet; Eberconazol; Eberconazolum

IUPAC/Chemical Name: 1-(2,4-dichloro-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-1H-imidazole nitrate


InChi Code: InChI=1S/C18H14Cl2N2.HNO3/c19-14-9-13-6-5-12-3-1-2-4-15(12)18(17(13)16(20)10-14)22-8-7-21-11-22;2-1(3)4/h1-4,7-11,18H,5-6H2;(H,2,3,4)

SMILES Code: ClC1=C(C(N2C=CN=C2)C3=CC=CC=C3CC4)C4=CC(Cl)=C1.[O-][N+](O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:

Additional Information

Related CAS#

128326-82-9(Eberconazole )
130104-32-4(Eberconazole Nitrate)


1: Gnaneshwar R, Kumar AS, Carol F, Martis J, Jerajani HR, Kuruvila M, Latha MS, Krishnankutty B. The Efficacy and Safety of Eberconazole Nitrate 1% and Mometasone Furoate 0.1% w/w Cream in Subjects with Inflamed Cutaneous Mycoses. Rev Recent Clin Trials. 2015;10(2):161-70. PubMed PMID: 26216438.

2: Choudhary SV, Aghi T, Bisati S. Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris. Indian Dermatol Online J. 2014 Apr;5(2):128-31. doi: 10.4103/2229-5178.131079. PubMed PMID: 24860743; PubMed Central PMCID: PMC4030336.

3: Repiso Montero T, López S, Rodríguez C, del Rio R, Badell A, Gratacós MR. Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: multicenter, randomized, double-blind, comparative trial with miconazole 2% cream. Int J Dermatol. 2006 May;45(5):600-4. PubMed PMID: 16700802.

4: Bothiraja C, Gholap AD, Shaikh KS, Pawar AP. Investigation of ethyl cellulose microsponge gel for topical delivery of eberconazole nitrate for fungal therapy. Ther Deliv. 2014 Jul;5(7):781-94. doi: 10.4155/tde.14.43. PubMed PMID: 25287385.

5: Eberconazole (Eberconazol, Eberconazole nitrate, WAS 2160). Drugs R D. 2002;3(5):352-4. PubMed PMID: 12455157.

6: Sharma N, Rao SS, Vaghela B. Validated Stability-indicating High-performance Liquid Chromatographic Method for Estimation of Degradation Behaviour of Eberconazole Nitrate and Mometasone Furoate in Cream Formulation. Indian J Pharm Sci. 2013 Jan;75(1):76-82. doi: 10.4103/0250-474X.113530. PubMed PMID: 23901164; PubMed Central PMCID: PMC3719153.