Naproxen etemesil

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MedKoo CAT#: 326961

CAS#: 385800-16-8

Description: Naproxen etemesil, also known as LT-NS-001; MX-1094; LTNS-001, is a cyclooxygenase (COX) inhibitor potentially for the treatment of osteoarthritis. Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active naproxen once absorbed. Naproxen etemesil was associated with significantly lower gastroduodenal mucosal injury compared with naproxen after 7 days of exposure.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-09-22. Prices are subject to change without notice.

Naproxen etemesil is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 326961
Name: Naproxen etemesil
CAS#: 385800-16-8
Chemical Formula: C17H20O5S
Exact Mass: 336.1031
Molecular Weight: 336.402
Elemental Analysis: C, 60.70; H, 5.99; O, 23.78; S, 9.53


Synonym: Naproxen etemesil; LT-NS-001; MX-1094; LTNS-001; LT-NS001; MX1094; LTNS001.

IUPAC/Chemical Name: 2-(methylsulfonyl)ethyl (S)-2-(6-methoxynaphthalen-2-yl)propanoate

InChi Key: JGBUBSOKFSVXKS-LBPRGKRZSA-N

InChi Code: InChI=1S/C17H20O5S/c1-12(17(18)22-8-9-23(3,19)20)13-4-5-15-11-16(21-2)7-6-14(15)10-13/h4-7,10-12H,8-9H2,1-3H3/t12-/m0/s1

SMILES Code: O=C(OCCS(=O)(C)=O)[C@@H](C)C1=CC=C2C=C(OC)C=CC2=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001