WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 326952
CAS#: 20559-55-1
Description: Oxibendazole, also known as SK&F-30310, SKF-30310, is a DNA polymerase inhibitor potentially for the treatment of helminth intestinal infections. Oxibendazole is laso used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. It is usually white to yellowish in appearance.
MedKoo Cat#: 326952
Name: Oxibendazole
CAS#: 20559-55-1
Chemical Formula: C12H15N3O3
Exact Mass: 249.1113
Molecular Weight: 249.27
Elemental Analysis: C, 57.82; H, 6.07; N, 16.86; O, 19.26
Synonym: Oxibendazole; SK&F-30310; SK&F30310; SK&F 30310; SKF-30310; SKF30310; SKF 30310. Anthelcide EQ; Loditac.
IUPAC/Chemical Name: methyl (5-propoxy-1H-benzo[d]imidazol-2-yl)carbamate
InChi Key: RAOCRURYZCVHMG-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
SMILES Code: O=C(OC)NC1=NC2=CC(OCCC)=CC=C2N1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 249.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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10: Tolliver SC, Lyons ET, Drudge JH, Stamper S, Granstrom DE. Critical tests of thiabendazole, oxibendazole, and oxfendazole for drug resistance of population-B equine small strongyles (1989 and 1990). Am J Vet Res. 1993 Jun;54(6):908-13. PubMed PMID: 8323061.
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17: Bauer C, Bürger HJ. Efficacy of an oxibendazole-trichlorfon paste formulation against third stage larvae of Gasterophilus intestinalis and its safety in horses. Vet Rec. 1986 Sep 20;119(12):294-6. PubMed PMID: 3535229.
18: Drudge JH, Lyons ET, Tolliver SC, Swerczek TW. Use of oxibendazole for control of cambendazole-resistant small strongyles in a band of ponies: a six-year study. Am J Vet Res. 1985 Dec;46(12):2507-11. PubMed PMID: 4083584.
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