WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 326935
Description: Fasoracetam, also known as NS-105; NFC-1; LAM-105, is a GABA receptor modulator potentially for the treatment of attention deficit hyperactivity disorder. It is a nootropic, and has been in a clinical trial for attention deficit hyperactivity disorder. In in vitro studies on mouse neurons, fasoracetam modulated mGluR II/III activity. In studies in rats, it blocked memory disruptions caused by baclofen, a GABAB agonist and upregulated production of GABAB receptors after repeat dosing.
MedKoo Cat#: 326935
Chemical Formula: C10H16N2O2
Exact Mass: 196.1212
Molecular Weight: 196.25
Elemental Analysis: C, 61.20; H, 8.22; N, 14.27; O, 16.30
Related CAS #: 1618109-51-5 (tartrate) 2055646-53-0 (hydrate) 110958-19-5
Synonym: Fasoracetam; N-(5-Oxo-D-prolyl)piperidine; NS-105; NFC-1; LAM-105.
IUPAC/Chemical Name: (R)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)piperidine
InChi Key: GOWRRBABHQUJMX-MRVPVSSYSA-N
InChi Code: InChI=1S/C10H16N2O2/c13-9-5-4-8(11-9)10(14)12-6-2-1-3-7-12/h8H,1-7H2,(H,11,13)/t8-/m1/s1
SMILES Code: O=C(N1CCCCC1)[C@@H](CC2)NC2=O
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8: Shimidzu T, Itoh Y, Oka M, Ishima T, Ukai Y, Yoshikuni Y, Kimura K. Effect of a novel cognition enhancer NS-105 on learned helplessness in rats: possible involvement of GABA(B) receptor up-regulation after repeated treatment. Eur J Pharmacol. 1997 Nov 12;338(3):225-32. PubMed PMID: 9424016.
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