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MedKoo CAT#: 326900
CAS#: 36589-58-9 (Sodium)
Description: Eprodisate, also known as 3-PDS; NC-503; 3PDS, is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate. This prevents the formation of amyloid deposits in certain organs, especially the kidneys, in AA amyloidosis.
MedKoo Cat#: 326900
Name: Eprodisate Sodium
CAS#: 36589-58-9 (Sodium)
Chemical Formula: C3H6Na2O6S2
Exact Mass:
Molecular Weight: 248.1745
Elemental Analysis: C, 14.52; H, 2.44; Na, 18.53; O, 38.68; S, 25.84
Synonym: 3-PDS; NC-503; 3PDS; Eprodisate Sodium; Kiacta.
IUPAC/Chemical Name: 1,3-Propanedisulfonic acid, disodium salt
InChi Key: DKGJFKPIUSHDIT-UHFFFAOYSA-L
InChi Code: InChI=1S/C3H8O6S2.2Na/c4-10(5,6)2-1-3-11(7,8)9;;/h1-3H2,(H,4,5,6)(H,7,8,9);;/q;2*+1/p-2
SMILES Code: O=S(CCCS(=O)([O-])=O)([O-])=O.[Na+].[Na+]
Related CAS#
21668-77-9(Eprodisate)
36589-58-9(Eprodisate Sodium)
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