Navoximod (free base)

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 327017

CAS#: 1402837-78-8 (free base)

Description: Navoximod, also known as IDO-IN-7 and NLG-1488, is an indoleamine 2,3-dioxygenase (IDO) inhibitor. It is also used as an immunomodulator and an antineoplastic.


Price and Availability

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Navoximod (IDO-IN-7) is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 327017
Name: Navoximod (free base)
CAS#: 1402837-78-8 (free base)
Chemical Formula: C18H21FN2O2
Exact Mass: 316.1587
Molecular Weight: 316.3764
Elemental Analysis: C, 68.34; H, 6.69; F, 6.01; N, 8.85; O, 10.11


Related CAS #: 1793075-63-4 (phosphate)   1402837-78-8 (free base)    

Synonym: Navoximod; IDO-IN-7; IDOIN7; IDO IN 7; Navoximod Phosphate; NLG-1488; NLG 1488; NLG1488.

IUPAC/Chemical Name: (1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol

InChi Key: YGACXVRLDHEXKY-WXRXAMBDSA-N

InChi Code: InChI=1S/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11-,12-,15-,17+/m0/s1

SMILES Code: O[C@@H]([C@H]1CC[C@H](O)CC1)C[C@@H](C2=C3C=CC=C2F)N4C3=CN=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

Related CAS#
1402837-78-8 (Navoximod free base);
1793075-63-4 (Navoximod phosphate)