WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526823

CAS#: 23146-22-7

Description: IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 90 2 Weeks
25mg USD 150 2 Weeks
50mg USD 250 2 Weeks
100mg USD 450 2 Weeks
200mg USD 750 2 Weeks
500mg USD 1350 2 Weeks
1g USD 2250 2 Weeks
2g USD 3850 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-26. Prices are subject to change without notice.

IQ-1S, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 526823
Name: IQ-1S
CAS#: 23146-22-7
Chemical Formula: C15H9N3O
Exact Mass: 247.0746
Molecular Weight: 247.257
Elemental Analysis: C, 72.87; H, 3.67; N, 16.99; O, 6.47

Synonym: IQ-1S

IUPAC/Chemical Name: 11H-Indeno[1,2-b]quinoxalin-11-one oxime


InChi Code: InChI=1S/C15H9N3O/c19-18-14-10-6-2-1-5-9(10)13-15(14)17-12-8-4-3-7-11(12)16-13/h1-8,19H/b18-14+

SMILES Code: O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Atochin DN, Schepetkin IA, Khlebnikov AI, Seledtsov VI, Swanson H, Quinn MT,
Huang PL. A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor
protects against cerebral ischemia-reperfusion injury in mice. Neurosci Lett.
2016 Apr 8;618:45-9. doi: 10.1016/j.neulet.2016.02.033. Epub 2016 Feb 26. PubMed
PMID: 26923672.

2: Schepetkin IA, Kirpotina LN, Hammaker D, Kochetkova I, Khlebnikov AI, Lyakhov
SA, Firestein GS, Quinn MT. Anti-Inflammatory Effects and Joint Protection in
Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun
N-Terminal Kinase Inhibitor. J Pharmacol Exp Ther. 2015 Jun;353(3):505-16. doi:
10.1124/jpet.114.220251. Epub 2015 Mar 17. PubMed PMID: 25784649; PubMed Central
PMCID: PMC4429673.