JNJ-1661010
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525305

CAS#: 681136-29-8

Description: JNJ-1661010 is a selective, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 = 12 nM). JNJ-1661010 is a brain penetrant and active in vivo.


Price and Availability

Size
Price

10mg
USD 240
Size
Price

25mg
USD 410
Size
Price

50mg
USD 750

JNJ-1661010, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525305
Name: JNJ-1661010
CAS#: 681136-29-8
Chemical Formula: C19H19N5OS
Exact Mass: 365.13103
Molecular Weight: 365.45
Elemental Analysis: C, 62.44; H, 5.24; N, 19.16; O, 4.38; S, 8.77


Synonym: JNJ-1661010; JNJ 1661010; JNJ1661010.

IUPAC/Chemical Name: 1-Piperazinecarboxamide, N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-

InChi Key: BHBOSTKQCZEAJM-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H19N5OS/c25-18(20-16-9-5-2-6-10-16)23-11-13-24(14-12-23)19-21-17(22-26-19)15-7-3-1-4-8-15/h1-10H,11-14H2,(H,20,25)

SMILES Code: O=C(N1CCN(C2=NC(C3=CC=CC=C3)=NS2)CC1)NC4=CC=CC=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Karbarz MJ, Luo L, Chang L, Tham CS, Palmer JA, Wilson SJ, Wennerholm ML, Brown SM, Scott BP, Apodaca RL, Keith JM, Wu J, Breitenbucher JG, Chaplan SR, Webb M. Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. Anesth Analg. 2009 Jan;108(1):316-29. doi: 10.1213/ane.0b013e31818c7cbd. PubMed PMID: 19095868.