Faropenem medoxomil

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 326766

CAS#: 141702-36-5 (medoxomil); 106559-89-1 (Faropenem)

Description: Faropenem medoxomil, also known as Faropenem daloxate or Faropenem medoxil, is an orally active beta-lactam antibiotic belonging to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase. Faropenem medoxomil is a prodrug of Faropenem.

Chemical Structure

Faropenem medoxomil
CAS# 141702-36-5 (medoxomil); 106559-89-1 (Faropenem)

Theoretical Analysis

MedKoo Cat#: 326766
Name: Faropenem medoxomil
CAS#: 141702-36-5 (medoxomil); 106559-89-1 (Faropenem)
Chemical Formula: C17H19NO8S
Exact Mass: 397.0831
Molecular Weight: 397.398
Elemental Analysis: C, 51.38; H, 4.82; N, 3.52; O, 32.21; S, 8.07

Price and Availability

Size Price Availability Quantity
10.0mg USD 425.0 2 Weeks
100.0mg USD 1240.0 2 Weeks
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Synonym: A0026; A-0026; A 0026; Faropenem medoxomil; Faropenem daloxate; Faropenem medoxil.

IUPAC/Chemical Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-((R)-1-hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate


InChi Code: InChI=1S/C17H19NO8S/c1-7(19)11-14(20)18-12(13(27-15(11)18)9-4-3-5-23-9)16(21)24-6-10-8(2)25-17(22)26-10/h7,9,11,15,19H,3-6H2,1-2H3/t7-,9-,11+,15-/m1/s1

SMILES Code: O=C(C(N12)=C([C@@H]3OCCC3)S[C@]2([H])[C@@H]([C@H](O)C)C1=O)OCC4=C(C)OC(O4)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 397.398 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Faqi AS, Lanphear C, Gill S, Colagiovanni DB. Juvenile toxicity study of faropenem medoxomil in beagle puppies. Reprod Toxicol. 2010 Dec;30(4):619-24. doi: 10.1016/j.reprotox.2010.07.010. Epub 2010 Aug 11. PubMed PMID: 20708074.

2: Faropenem medoxomil: A0026, BAY 56-6854, BAY 566854, faropenem daloxate, SUN 208, SUN A0026. Drugs R D. 2008;9(2):115-24. Review. PubMed PMID: 18298129.

3: Gettig JP, Crank CW, Philbrick AH. Faropenem medoxomil. Ann Pharmacother. 2008 Jan;42(1):80-90. Epub 2007 Dec 19. Review. PubMed PMID: 18094341.

4: Hadley JA, Tillotson GS, Tosiello R, Echols RM. Faropenem medoxomil: a treatment option in acute bacterial rhinosinusitis. Expert Rev Anti Infect Ther. 2006 Dec;4(6):923-37. Review. PubMed PMID: 17181408.

5: Upchurch J, Rosemore M, Tosiello R, Kowalsky S, Echols R. Randomized double-blind study comparing 7- and 10-day regimens of faropenem medoxomil with a 10-day cefuroxime axetil regimen for treatment of acute bacterial sinusitis. Otolaryngol Head Neck Surg. 2006 Oct;135(4):511-7. PubMed PMID: 17011409.