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MedKoo CAT#: 406788

CAS#: 1185763-69-2

Description: NVP-BVU972, also known as BVN-972, is a selective and potent inhibitor of c-Met with IC50 of 14 nM. BVN-972 displays IC50 values more than 1000 nM in other kinases such as the most closely related kinase recepteur d'origine nantais (RON).

Price and Availability

Size Price Shipping out time Quantity
10mg USD 710 2 Weeks
50mg USD 1860 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-22. Prices are subject to change without notice.

NVP-BVU972, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 406788
Name: NVP-BVU972
CAS#: 1185763-69-2
Chemical Formula: C20H16N6
Exact Mass: 340.1436
Molecular Weight: 340.39
Elemental Analysis: C, 70.57; H, 4.74; N, 24.69

Synonym: NVP-BVU972; NVP-BVU 972; NVP-BVU-972; BVU-972; BVU 972; BVU972.

IUPAC/Chemical Name: 6-[[6-(1-methylpyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]quinoline


InChi Code: InChI=1S/C20H16N6/c1-25-13-16(11-23-25)19-6-7-20-22-12-17(26(20)24-19)10-14-4-5-18-15(9-14)3-2-8-21-18/h2-9,11-13H,10H2,1H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Shin JS, Hong SW, Moon JH, Kim JS, Jung KA, Kim SM, Lee DH, Kim I, Yoon SJ,
Lee CG, Choi EK, Lee JY, Kim KP, Hong YS, Lee JL, Kim B, Choi EK, Lee JS, Jin DH,
Kim TW. NPS-1034, a novel MET inhibitor, inhibits the activated MET receptor and
its constitutively active mutants. Invest New Drugs. 2014 Jun;32(3):389-99. doi:
10.1007/s10637-013-0039-4. Epub 2013 Oct 31. PubMed PMID: 24173966.

2: Tiedt R, Degenkolbe E, Furet P, Appleton BA, Wagner S, Schoepfer J, Buck E,
Ruddy DA, Monahan JE, Jones MD, Blank J, Haasen D, Drueckes P, Wartmann M,
McCarthy C, Sellers WR, Hofmann F. A drug resistance screen using a selective MET
inhibitor reveals a spectrum of mutations that partially overlap with activating
mutations found in cancer patients. Cancer Res. 2011 Aug 1;71(15):5255-64. doi:
10.1158/0008-5472.CAN-10-4433. Epub 2011 Jun 22. PubMed PMID: 21697284.