Nanterinone

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525727

CAS#: 102791-47-9

Description: Nanterinone is a novel positive inotropic and balanced-type vasodilating drug, only partially based on phosphodiesterase III inhibition. Nanterinone exhibits acute hemodynamic effects in patients with mild to moderate heart failure.


Price and Availability

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Nanterinone is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525727
Name: Nanterinone
CAS#: 102791-47-9
Chemical Formula: C15H15N3O
Exact Mass: 253.12151
Molecular Weight: 253.305
Elemental Analysis: C, 71.13; H, 5.97; N, 16.59; O, 6.32


Synonym: UK 61260; UK-61260; UK61260; Nanterinone

IUPAC/Chemical Name: 6-(2,4-dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one

SMILES Code: O=C1NC2=C(C=C(N3C=C(C)N=C3C)C=C2C)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Remme WJ, van der Ent M, Bartels GL, van Schelven D, van Hoogenhuyze DC, Krauss XH, Kruijssen HA, Storm CJ. Acute hemodynamic effects and preload-dependent cardiovascular profile of the partial phosphodiesterase inhibitor nanterinone in patients with mild to moderate heart failure. Cardiovasc Drugs Ther. 1996 May;10(2):137-44. PubMed PMID: 8842505.