Xylazine
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526577

CAS#: 7361-61-7

Description: Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats.


Price and Availability

Size
Price

1g
USD 150
10g
USD 650
Size
Price

2g
USD 250
25g
USD 950
Size
Price

5g
USD 450
50g
USD 1650

Xylazine, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 526577
Name: Xylazine
CAS#: 7361-61-7
Chemical Formula: C12H16N2S
Exact Mass: 220.1034
Molecular Weight: 220.334
Elemental Analysis: C, 65.42; H, 7.32; N, 12.71; S, 14.55


Synonym: BAY 1470; BAY1470; BAY-1470; Xylazine; Primazine; Rometar; Sedomin

IUPAC/Chemical Name: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine

InChi Key: BPICBUSOMSTKRF-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)

SMILES Code: 2,6-Xylidine, N-(5,6-dihydro-4H-1,3-thiazinyl)-


Technical Data

Appearance:
White to off-white crystalline powder.

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Ruiz-Colón K, Chavez-Arias C, Díaz-Alcalá JE, Martínez MA. Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. Forensic Sci Int. 2014 Jul;240:1-8. doi: 10.1016/j.forsciint.2014.03.015. Epub 2014 Mar 26. Review. PubMed PMID: 24769343.

2: Mittleman RE, Hearn WL, Hime GW. Xylazine toxicity--literature review and report of two cases. J Forensic Sci. 1998 Mar;43(2):400-2. Review. PubMed PMID: 9544551.

3: Fyffe JJ. Effects of xylazine on humans: a review. Aust Vet J. 1994 Sep;71(9):294-5. Review. PubMed PMID: 7818438.

4: Schmidt-Oechtering GU, Alef M, Röcken M. [Anesthesia of horses with xylazine and ketamine. 2. Anesthesia in adult horses]. Tierarztl Prax. 1990 Feb;18(1):47-52. Review. German. PubMed PMID: 2183391.

5: Greene SA, Thurmon JC. Xylazine--a review of its pharmacology and use in veterinary medicine. J Vet Pharmacol Ther. 1988 Dec;11(4):295-313. Review. PubMed PMID: 3062194.

6: Capraro AJ, Wiley JF 2nd, Tucker JR. Severe intoxication from xylazine inhalation. Pediatr Emerg Care. 2001 Dec;17(6):447-8. Review. PubMed PMID: 11753193.

7: Hoffmann U, Meister CM, Golle K, Zschiesche M. Severe intoxication with the veterinary tranquilizer xylazine in humans. J Anal Toxicol. 2001 May-Jun;25(4):245-9. Review. PubMed PMID: 11386637.

8: Chamberlain PL, Brynes SD. The regulatory status of xylazine for use in food-producing animals in the United States. J Vet Pharmacol Ther. 1998 Aug;21(4):322-9. Review. PubMed PMID: 9731956.

9: Schmidt-Oechtering GU, Becker K. [Old and new alpha 2-adrenoceptor agonists. 1. Xylazine and medetomidine]. Tierarztl Prax. 1992 Oct;20(5):447-58. Review. German. PubMed PMID: 1359676.

10: Gallanosa AG, Spyker DA, Shipe JR, Morris DL. Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants. Clin Toxicol. 1981 Jun;18(6):663-78. Review. PubMed PMID: 6115734.

11: Holmes AM, Clark WT. Xylazine for sedation of horses. N Z Vet J. 1977 Jun;25(6):159-61. Review. PubMed PMID: 351482.