BMS-194449

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524449

CAS#: 170686-12-1

Description: BMS-194449 is a full beta 3 agonist.

Chemical Structure

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BMS-194449
CAS# 170686-12-1
Instruction

Theoretical Analysis

MedKoo Cat#: 524449
Name: BMS-194449
CAS#: 170686-12-1
Chemical Formula: C24H24F4N2O6S
Exact Mass: 544.13
Molecular Weight: 544.520
Elemental Analysis: C, 52.94; H, 4.44; F, 13.96; N, 5.14; O, 17.63; S, 5.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: BMS-194449; BMS 194449; BMS194449; UNII-93ZDV2P17I; CHEMBL320915; 93ZDV2P17I; SCHEMBL7042103; BDBM50106794.

IUPAC/Chemical Name: (R)-N-(5-(2-((bis(4-(difluoromethoxy)phenyl)methyl)amino)-1-hydroxyethyl)-2-hydroxyphenyl)methanesulfonamide

InChi Key: FUKHGCVTMAEHRG-NRFANRHFSA-N

InChi Code: InChI=1S/C24H24F4N2O6S/c1-37(33,34)30-19-12-16(6-11-20(19)31)21(32)13-29-22(14-2-7-17(8-3-14)35-23(25)26)15-4-9-18(10-5-15)36-24(27)28/h2-12,21-24,29-32H,13H2,1H3/t21-/m0/s1

SMILES Code: CS(=O)(=O)Nc1cc(ccc1O)[C@H](CNC(c2ccc(cc2)OC(F)F)c3ccc(cc3)OC(F)F)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 544.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Washburn WN, Sher PM, Poss KM, Girotra RN, McCann PJ, Gavai AV, Mikkilineni AB, Mathur A, Cheng P, Dejneka TC, Sun CQ, Wang TC, Harper TW, Russell AD, Slusarchyk DA, Skwish S, Allen GT, Hillyer DE, Frohlich BH, Abboa-Offei BE, Cap M, Waldron TL, George RJ, Tesfamariam B, Ciosek CP Jr, Ryono D, Young DA, Dickinson KE, Seymour AA, Arbeeny CM, Gregg RE. Beta 3 agonists. Part 1: evolution from inception to BMS-194449. Bioorg Med Chem Lett. 2001 Dec 3;11(23):3035-9. PubMed PMID: 11714605.