BAY-59-3074
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524385

CAS#: 406205-74-1

Description: BAY-59-3074 is a novel cannabinoid CB1/CB2 receptor partial agonist with analgesic properties. It displays anti-hyperalgesic and antiallodynic properties in rat models of chronic neuropathic and inflammatory pain.


Price and Availability

Size
Price

10mg
USD 150
100mg
USD 750
1g
USD 2850
Size
Price

25mg
USD 250
200mg
USD 950
2g
USD 3950
Size
Price

50mg
USD 450
500mg
USD 1650
5g
Ask price

BAY-59-3074, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 524385
Name: BAY-59-3074
CAS#: 406205-74-1
Chemical Formula: C21H21FN8O
Exact Mass: 420.18224
Molecular Weight: 420.44
Elemental Analysis: C, 59.99; H, 5.03; F, 4.52; N, 26.65; O, 3.81


Synonym: BAY-59-3074; BAY 59-3074; BAY59-3074

IUPAC/Chemical Name: 1-Butanesulfonic acid, 4,4,4-trifluoro-, 3-(2-cyano-3-(trifluoromethyl)phenoxy)phenyl ester

InChi Key: LWUSZIVDPJPVBW-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H13F6NO4S/c19-17(20,21)8-3-9-30(26,27)29-13-5-1-4-12(10-13)28-16-7-2-6-15(14(16)11-25)18(22,23)24/h1-2,4-7,10H,3,8-9H2

SMILES Code: O=S(CCCC(F)(F)F)(OC1=CC=CC(OC2=CC=CC(C(F)(F)F)=C2C#N)=C1)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Teng H, Thakur GA, Makriyannis A. Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5999-6002. doi: 10.1016/j.bmcl.2011.07.017. Epub 2011 Jul 23. PubMed PMID: 21880487; PubMed Central PMCID: PMC3693451.

2: De Vry J, Jentzsch KR. Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat. Eur J Pharmacol. 2004 Nov 28;505(1-3):127-33. PubMed PMID: 15556145.

3: De Vry J, Denzer D, Reissmueller E, Eijckenboom M, Heil M, Meier H, Mauler F. 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novel cannabinoid Cb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic effects. J Pharmacol Exp Ther. 2004 Aug;310(2):620-32. Epub 2004 May 12. PubMed PMID: 15140913.