Bay-02752

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524378

CAS#: 78991-74-9

Description: Bay-02752 is a hypolipidemic drug. It has been demonstrated in rats to inhibit intestinal cholesterol absorption.


Price and Availability

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Bay-02752, purity > 98%, is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 524378
Name: Bay-02752
CAS#: 78991-74-9
Chemical Formula: C31H44N4O2
Exact Mass: 504.34643
Molecular Weight: 504.71
Elemental Analysis: C, 73.77; H, 8.79; N, 11.10; O, 6.34


Synonym: Bay-02752; Bay 02752; Bay02752;

IUPAC/Chemical Name: 1H-Indole-1-carboxamide, N,N'-1,11-undecanediylbis(2,3-dihydro-2-methyl-

InChi Key: GOJXYVFOLUSEAA-UHFFFAOYSA-N

InChi Code: InChI=1S/C31H44N4O2/c1-24-22-26-16-10-12-18-28(26)34(24)30(36)32-20-14-8-6-4-3-5-7-9-15-21-33-31(37)35-25(2)23-27-17-11-13-19-29(27)35/h10-13,16-19,24-25H,3-9,14-15,20-23H2,1-2H3,(H,32,36)(H,33,37)

SMILES Code: CC1Cc2ccccc2N1C(=O)NCCCCCCCCCCCNC(=O)N3c4ccccc4CC3C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Laccabue D, Tortoreto M, Veneroni S, Perego P, Scanziani E, Zucchetti M, Zaffaroni M, D'Incalci M, Bombardelli E, Zunino F, Pratesi G. A novel taxane active against an orthotopically growing human glioma xenograft. Cancer. 2001 Dec 15;92(12):3085-92. PubMed PMID: 11753988.

2: Harnett KM, Walsh CT, Zhang LH. Effects of Bay o 2752, a hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification. J Pharmacol Exp Ther. 1989 Nov;251(2):502-9. PubMed PMID: 2810110.

3: Kritchevsky D, Klurfeld DM. Influence of N,N'-(1,11-undecandiyl) bis (2,3-dihydro-2-methyl-1H-indole-1-carboxamide) (BAY 02752) on gallstone formation and regression in hamsters. Pharmacol Res Commun. 1987 Oct;19(10):679-84. PubMed PMID: 3441483.