Quetiapine hemifumarate
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MedKoo CAT#: 318598

CAS#: 111974-72-2 (hemifumarate)

Description: Quetiapine, also known as ICI 204636, is an antipsychotic agent. It targets the serotonin 5-HT2 receptor, histamine H1 receptor, adreneragic alpha1 and alpha2 rectors as well as the dopamine D1 and D2 receptors. It is used in the treatment of schizophrenia, bipolar disorder and depressive disorder.


Price and Availability

Size
Price

2g
USD 150
20g
USD 850
Size
Price

5g
USD 250
Size
Price

10g
USD 450

Quetiapine Fumarate, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 318598
Name: Quetiapine hemifumarate
CAS#: 111974-72-2 (hemifumarate)
Chemical Formula: C46H54N6O8S2
Exact Mass:
Molecular Weight: 883.09
Elemental Analysis: C, 62.56; H, 6.16; N, 9.52; O, 14.49; S, 7.26


Related CAS #: 111974-72-2 (hemifumarate)   111974-69-7 (free base)    

Synonym: ICI 204,636; IC-204,636; ICI204,636; ICI-204636; ICI 204636; ICI204636; Quetiapine Fumarate; Quetiapine hemifumarate; Seroquel XR.

IUPAC/Chemical Name: 2-(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethan-1-ol; fumarate (2:1)

InChi Key: ZTHJULTYCAQOIJ-WXXKFALUSA-N

InChi Code: InChI=1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

SMILES Code: C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=CC(=O)O)C(=O)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

Related CAS#
CAS# 111974-72-2 ( Quetiapine hemifumarate)
CAS#111974-69-7 ( Quetiapine free base).


References

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2: Upadhyay P, Trivedi J, Pundarikakshudu K, Sheth N. Comparative study between
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7: Bonafede M, Locklear JC, Wahlqvist P, Fajutrao L, Szamosi J, Pan K, Eriksson
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with major depressive disorder: secondary analyses in subgroups of patients
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19: Khan A, Atkinson S, Mezhebovsky I, She F, Leathers T, Pathak S.
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