TUG-770
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MedKoo CAT#: 522663

CAS#: 1402601-82-4

Description: TUG-770 is a Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes. Free fatty acid receptor 1 (FFA1 or GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and currently attracts high interest as a new target for the treatment of type 2 diabetes.


Price and Availability

Size
Price

200mg
USD 1750
2g
USD 4950
Size
Price

500mg
USD 2650
5g
Ask price
Size
Price

1g
USD 3250

TUG-770, purity > 98%, is in stock. Minimum order is 200mg. Current shipping out time is about 2 weeks after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 522663
Name: TUG-770
CAS#: 1402601-82-4
Chemical Formula: C19H14FNO2
Exact Mass: 307.1009
Molecular Weight: 307.3244
Elemental Analysis: C, 74.26; H, 4.59; F, 6.18; N, 4.56; O, 10.41


Synonym: TUG-770; TUG 770; TUG770.

IUPAC/Chemical Name: 3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluorophenyl]propanoic acid

SMILES Code: O=C(O)CCC1=CC=C(C#CC2=CC=CC=C2CC#N)C=C1F


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Christiansen E, Hansen SV, Urban C, Hudson BD, Wargent ET, Grundmann M,
Jenkins L, Zaibi M, Stocker CJ, Ullrich S, Kostenis E, Kassack MU, Milligan G,
Cawthorne MA, Ulven T. Discovery of TUG-770: A Highly Potent Free Fatty Acid
Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes. ACS Med Chem
Lett. 2013 May 9;4(5):441-445. Epub 2013 Apr 8. PubMed PMID: 23687558; PubMed
Central PMCID: PMC3654565.