Ibuprofen
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 318050

CAS#: 15687-27-1

Description: Ibuprofen, from isobutylphenylpropanoic acid, is a nonsteroidal anti-inflammatory drug (NSAID) used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis.


Price and Availability

Size
Price

1g
USD 150
10g
USD 380
100g
USD 650
1kg
Ask price
Size
Price

2g
USD 250
20g
USD 450
200g
USD 850
2kg
Ask price
Size
Price

5g
USD 350
50g
USD 550
500g
USD 1050

Ibuprofen, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 318050
Name: Ibuprofen
CAS#: 15687-27-1
Chemical Formula: C13H18O2
Exact Mass: 206.1307
Molecular Weight: 206.2808
Elemental Analysis: C, 75.69; H, 8.80; O, 15.51


Related CAS #: 15687-27-1   57469-77-9 (lysine)   57469-82-6 (ariginine)    

Synonym: Ibuprofen, Advil, Motrin, Nurofen, Brufen

IUPAC/Chemical Name: 2-[4-(2-methylpropyl)phenyl]propanoic acid

InChi Key: HEFNNWSXXWATRW-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

SMILES Code: CC(C1=CC=C(CC(C)C)C=C1)C(O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Moore RA, Derry S, Wiffen PJ, Straube S, Aldington DJ. Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions. Eur J Pain. 2015 Oct;19(9):1213-23. doi: 10.1002/ejp.649. Epub 2014 Dec 22. Review. PubMed PMID: 25530283.

2: Derry S, Wiffen PJ, Moore RA. Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults. Cochrane Database Syst Rev. 2015 Jul 14;7:CD011509. doi: 10.1002/14651858.CD011509.pub2. Review. PubMed PMID: 26171993.

3: Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants. Cochrane Database Syst Rev. 2015 Feb 18;2:CD003481. doi: 10.1002/14651858.CD003481.pub6. Review. PubMed PMID: 25692606.

4: Koh W, Nguyen KP, Jahr JS. Intravenous non-opioid analgesia for peri- and postoperative pain management: a scientific review of intravenous acetaminophen and ibuprofen. Korean J Anesthesiol. 2015 Feb;68(1):3-12. doi: 10.4097/kjae.2015.68.1.3. Epub 2015 Jan 28. Review. PubMed PMID: 25664148; PubMed Central PMCID: PMC4318862.

5: Kelly LE, Sommer DD, Ramakrishna J, Hoffbauer S, Arbab-Tafti S, Reid D, Maclean J, Koren G. Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial. Pediatrics. 2015 Feb;135(2):307-13. doi: 10.1542/peds.2014-1906. PubMed PMID: 25624387.

6: Derry S, Karlin SM, Moore RA. Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. Cochrane Database Syst Rev. 2015 Feb 5;2:CD010107. doi: 10.1002/14651858.CD010107.pub3. Review. PubMed PMID: 25927097.

7: Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DW. Combined and alternating paracetamol and ibuprofen therapy for febrile children. Evid Based Child Health. 2014 Sep;9(3):675-729. doi: 10.1002/ebch.1978. Review. PubMed PMID: 25236309.

8: Moore N, Salvo F, Duong M, Blin P, Pariente A. Cardiovascular risks associated with low-dose ibuprofen and diclofenac as used OTC. Expert Opin Drug Saf. 2014 Feb;13(2):167-79. doi: 10.1517/14740338.2014.846324. Epub 2013 Nov 21. Review. PubMed PMID: 24256349.

9: Pacifici GM. Clinical pharmacology of ibuprofen and indomethacin in preterm infants with patent ductus arteriosus. Curr Pediatr Rev. 2014;10(3):216-37. Review. PubMed PMID: 25088343.

10: Moore RA, Derry S, Straube S, Ireson-Paine J, Wiffen PJ. Faster, higher, stronger? Evidence for formulation and efficacy for ibuprofen in acute pain. Pain. 2014 Jan;155(1):14-21. doi: 10.1016/j.pain.2013.08.013. Epub 2013 Aug 19. Review. PubMed PMID: 23969325.

11: Pacifici GM. Differential renal adverse effects of ibuprofen and indomethacin in preterm infants: a review. Clin Pharmacol. 2014 Jul 31;6:111-6. doi: 10.2147/CPAA.S59376. eCollection 2014. Review. PubMed PMID: 25114597; PubMed Central PMCID: PMC4124049.

12: Bailey E, Worthington HV, van Wijk A, Yates JM, Coulthard P, Afzal Z. Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth. Cochrane Database Syst Rev. 2013 Dec 12;12:CD004624. doi: 10.1002/14651858.CD004624.pub2. Review. PubMed PMID: 24338830.

13: Patel A, Bell M, O'Connor C, Inchley A, Wibawa J, Lane ME. Delivery of ibuprofen to the skin. Int J Pharm. 2013 Nov 30;457(1):9-13. doi: 10.1016/j.ijpharm.2013.09.019. Epub 2013 Sep 21. Review. PubMed PMID: 24064201.

14: Derry S, Best J, Moore RA. Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. Cochrane Database Syst Rev. 2013 Oct 23;10:CD007550. doi: 10.1002/14651858.CD007550.pub3. Review. PubMed PMID: 24151035.

15: Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DW. Combined and alternating paracetamol and ibuprofen therapy for febrile children. Cochrane Database Syst Rev. 2013 Oct 30;10:CD009572. doi: 10.1002/14651858.CD009572.pub2. Review. PubMed PMID: 24174375.

16: Deeks ED. Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy. Clin Drug Investig. 2013 Sep;33(9):689-97. doi: 10.1007/s40261-013-0113-x. Review. PubMed PMID: 23881568.

17: Sarzi-Puttini P, Atzeni F, Lanata L, Bagnasco M. Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis. Clin Exp Rheumatol. 2013 Sep-Oct;31(5):731-8. Epub 2013 May 17. Review. PubMed PMID: 23711416.

18: Moore PA, Hersh EV. Combining ibuprofen and acetaminophen for acute pain management after third-molar extractions: translating clinical research to dental practice. J Am Dent Assoc. 2013 Aug;144(8):898-908. Review. PubMed PMID: 23904576.

19: Derry CJ, Derry S, Moore RA. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. Cochrane Database Syst Rev. 2013 Jun 24;6:CD010210. doi: 10.1002/14651858.CD010210.pub2. Review. PubMed PMID: 23794268.

20: Derry S, Derry CJ, Moore RA. Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults. Cochrane Database Syst Rev. 2013 Jun 26;6:CD010289. doi: 10.1002/14651858.CD010289.pub2. Review. PubMed PMID: 23801549.