Zicronapine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319862

CAS#: 170381-16-5

Description: Zicronapine, also known as Lu 31-130, is an atypical antipsychotic medication. Zicronapine exhibits monoaminergic activity and has a multi-receptorial profile. In vitro and in vivo it has shown potent antagonistic effects at dopamine D1, D2 and serotonin 5HT2A receptors.


Price and Availability

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Zicronapine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international). Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 319862
Name: Zicronapine
CAS#: 170381-16-5
Chemical Formula: C22H27ClN2
Exact Mass: 354.1863
Molecular Weight: 354.922
Elemental Analysis: C, 74.45; H, 7.67; Cl, 9.99; N, 7.89


Synonym: Lu 31-130; Lu31-130; Lu-31-130; Lu 31130; Lu31130; Lu-31130; Zicronapine.

IUPAC/Chemical Name: 4-((1R,3S)-6-chloro-3-phenyl-2,3-dihydro-1H-inden-1-yl)-1,2,2-trimethylpiperazine

InChi Key: BYPMJBXPNZMNQD-PZJWPPBQSA-N

InChi Code: InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3/t19-,21+/m0/s1

SMILES Code: CC1(C)N(C)CCN([C@@H]2C[C@@H](C3=CC=CC=C3)C4=C2C=C(Cl)C=C4)C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

In 2014 Lundbeck removed zicronapine from its development portfolio in favor of pursuing the more promising medicine Lu AF35700.