Fedovapagon

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319788

CAS#: 347887-36-9

Description: Fedovapagon, also known as VA106483 and VT483, is a potent, nonpeptidic vasopressin V2 receptor agonist. Vasopressin (AVP) is a hormone that stimulates an increase in water permeability through activation of V2 receptors in the kidney.


Price and Availability

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10mg
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100mg
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1g
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10g
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25mg
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200mg
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2g
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20g
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50mg
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500mg
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5g
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50g
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Fedovapagon is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 319788
Name: Fedovapagon
CAS#: 347887-36-9
Chemical Formula: C27H34N4O3
Exact Mass: 462.2631
Molecular Weight: 462.594
Elemental Analysis: C, 70.10; H, 7.41; N, 12.11; O, 10.38


Synonym: VA106483; VA-106483; VA 106483; VT483; VT-483; VT 483; Fedovapagon

IUPAC/Chemical Name: (S)-N2,N2-dimethyl-N1-(2-methyl-4-(2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)benzyl)pyrrolidine-1,2-dicarboxamide

InChi Key: RUOLFWZIFNQQGH-DEOSSOPVSA-N

InChi Code: InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1

SMILES Code: O=C(N1[C@H](C(N(C)C)=O)CCC1)NCC2=CC=C(C(N3CCCCC4=CC=CC=C43)=O)C=C2C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Yea CM, Allan CE, Ashworth DM, Barnett J, Baxter AJ, Broadbridge JD, Franklin
RJ, Hampton SL, Hudson P, Horton JA, Jenkins PD, Penson AM, Pitt GR, Rivière P,
Robson PA, Rooker DP, Semple G, Sheppard A, Haigh RM, Roe MB. New benzylureas as
a novel series of potent, nonpeptidic vasopressin V2 receptor agonists. J Med
Chem. 2008 Dec 25;51(24):8124-34. doi: 10.1021/jm8008162. PubMed PMID: 19053774.