Fasitibant chloride (HCl salt)

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319787

CAS#: 869880-33-1 (HCl salt); 1157852-02-2

Description: Fasitibant chloride, also known as MEN16132, is a potent and selective nonpeptide kinin B2 receptor antagonist. MEN16132 inhibited in a dose-dependent manner the bronchoconstriction induced by BK (10 nmol/kg i.v.). MEN16132 was more potent and possessed a longer duration of action as compared with the peptide B(2) receptor antagonist icatibant.


Price and Availability

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10mg
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1g
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10g
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25mg
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200mg
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2g
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20g
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50mg
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500mg
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5g
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Fasitibant chloride HCl salt is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 319787
Name: Fasitibant chloride (HCl salt)
CAS#: 869880-33-1 (HCl salt); 1157852-02-2
Chemical Formula: C36H50Cl4N6O6S
Exact Mass:
Molecular Weight: 836.692
Elemental Analysis: C, 51.68; H, 6.02; Cl, 16.95; N, 10.04; O, 11.47; S, 3.83


Synonym: MEN16132; MEN-16132; MEN 16132; Fasitibant chloride

IUPAC/Chemical Name: (S)-4-amino-5-(4-(4-((2,4-dichloro-3-(((2,4-dimethylquinolin-8-yl)oxy)methyl)phenyl)sulfonamido)tetrahydro-2H-pyran-4-carbonyl)piperazin-1-yl)-N,N,N-trimethyl-5-oxopentan-1-aminium chloride hydrochloride

InChi Key: QIAWOUUTKDMGTE-UJXPALLWSA-M

InChi Code: InChI=1S/C36H49Cl2N6O6S.2ClH/c1-24-22-25(2)40-33-26(24)8-6-10-30(33)50-23-27-28(37)11-12-31(32(27)38)51(47,48)41-36(13-20-49-21-14-36)35(46)43-17-15-42(16-18-43)34(45)29(39)9-7-19-44(3,4)5;;/h6,8,10-12,22,29,41H,7,9,13-21,23,39H2,1-5H3;2*1H/q+1;;/p-1/t29-;;/m0../s1

SMILES Code: O=C(N1CCN(C(C2(NS(=O)(C3=CC=C(Cl)C(COC4=C5N=C(C)C=C(C)C5=CC=C4)=C3Cl)=O)CCOCC2)=O)CC1)[C@@H](N)CCC[N+](C)(C)C.[H]Cl.[Cl-]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490