Sarecycline HCl
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MedKoo CAT#: 319682

CAS#: 1035979-44-2 (HCl)

Description: Sarecycline, also known as WC-3035 and P005672, is a novel, tetracycline-derived, narrow-spectrum antibiotic being developed for use as an oral once daily antibiotic treatment for patients suffering from moderate to severe acne vulgaris. Sarecycline was designed by Paratek as a narrow-spectrum antibiotic with anti-inflammatory activity and the potential for a favorable tolerability profile.


Price and Availability

Size
Price

25mg
USD 190
500mg
USD 1850
Size
Price

50mg
USD 350
1g
USD 3250
Size
Price

100mg
USD 650
5g
USD 7950

Sarecycline HCl, purity > 95%, is in stock. Current shipping out time is about 2 weeks after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 319682
Name: Sarecycline HCl
CAS#: 1035979-44-2 (HCl)
Chemical Formula: C24H30ClN3O8
Exact Mass:
Molecular Weight: 523.967
Elemental Analysis: C, 55.02; H, 5.77; Cl, 6.77; N, 8.02; O, 24.43


Related CAS #: 1035979-44-2 (HCl)   1035654-66-0 (free base)    

Synonym: WC-3035; WC 3035; WC3035; P005672; P-005672; P 005672; P005672 HCl; Sarecycline hydrochloride

IUPAC/Chemical Name: (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-7-((methoxy(methyl)amino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride

InChi Key: APPRLAGZQKOUFL-FIPJBXKNSA-N

InChi Code: InChI=1S/C24H29N3O8.ClH/c1-26(2)18-13-8-11-7-12-10(9-27(3)35-4)5-6-14(28)16(12)19(29)15(11)21(31)24(13,34)22(32)17(20(18)30)23(25)33;/h5-6,11,13,18,28,30-31,34H,7-9H2,1-4H3,(H2,25,33);1H/t11-,13-,18-,24-;/m0./s1

SMILES Code: O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C=CC(CN(OC)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>95% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Karpiuk I, Tyski S. Looking for new preparations for antibacterial therapy.
IV. New antimicrobial agents from the aminoglycoside, macrolide and tetracycline
groups in clinical trials. Przegl Epidemiol. 2015;69(4):723-9, 865-70. English,
Polish. PubMed PMID: 27139351.