GENZ-644282 TFA salt
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206482

CAS#: Unknown (TFA)

Description: Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.


Price and Availability

Size
Price

5mg
USD 90
50mg
USD 350
Size
Price

10mg
USD 150
100mg
USD 550
Size
Price

25mg
USD 250

GENZ-644282 TFA salt, purity > 98%, is in stock. The same day shipping out after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 206482
Name: GENZ-644282 TFA salt
CAS#: Unknown (TFA)
Chemical Formula: C24H22F3N3O7
Exact Mass:
Molecular Weight: 521.44921
Elemental Analysis: C, 55.28; H, 4.25; F, 10.93; N, 8.06; O, 21.48


Related CAS #: 529488-28-6 (free base)   Unknown (TFA)    

Synonym: GENZ-644282; GENZ644282; GENZ 644282; SAR402674; SAR 402674; SAR-402674.

IUPAC/Chemical Name: 2,3-dimethoxy-12-(2-(methylamino)ethyl)-[1,3]dioxolo[4',5':4,5]benzo[1,2-h]benzo[c][1,6]naphthyridin-13(12H)-one trifluoroacetic acid

InChi Key: QMZQFWGNILZXIV-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H21N3O5.C2HF3O2/c1-23-4-5-25-21-14-8-19-20(30-11-29-19)9-16(14)24-10-15(21)12-6-17(27-2)18(28-3)7-13(12)22(25)26;3-2(4,5)1(6)7/h6-10,23H,4-5,11H2,1-3H3;(H,6,7)

SMILES Code: O=C1N(CCNC)C2=C(C=NC3=CC(OCO4)=C4C=C32)C5=CC(OC)=C(OC)C=C15.O=C(O)C(F)(F)F


Technical Data

Appearance:
Yellow solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490