Bevantolol Hydrochloride
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317322

CAS#: 42864-78-8 (HCl)

Description: Bevantolol Hydrochloride is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.


Price and Availability

Size
Price

250mg
USD 350
Size
Price

1g
USD 1050
Size
Price

Bevantolol Hydrochloride purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 317322
Name: Bevantolol Hydrochloride
CAS#: 42864-78-8 (HCl)
Chemical Formula: C20H28ClNO4
Exact Mass:
Molecular Weight: 381.89
Elemental Analysis: C, 62.90; H, 7.39; Cl, 9.28; N, 3.67; O, 16.76


Related CAS #: 59170-23-9 (free base)   42864-78-8 (HCl)    

Synonym: Bevantolol Hydrochloride; Bevantolol HCl; Vantol; Cl 775; Cl775; Cl 775.

IUPAC/Chemical Name: 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol;hydrochloride

InChi Key: FJTKCFSPYUMXJB-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H27NO4.ClH/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3;/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3;1H

SMILES Code: OC(COC1=CC=CC(C)=C1)CNCCC2=CC=C(OC)C(OC)=C2.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Noshiro T, Miura Y, Yoshinaga K, Iimura O, Inagaki Y, Saruta T, Ishii M,
Yamazaki N, Arakawa K. Clinical evaluation of bevantolol hydrochloride in
patients with severe hypertension. The Cooperative Study Group on Bevantolol in
Japan. Int J Clin Pharmacol Ther. 1995 Apr;33(4):240-5. PubMed PMID: 7620695.

2: Shiraishi K, Moriya M, Miyake N, Takayanagi I. Alpha 1-adrenoceptor blocking
activities of bevantolol hydrochloride(NC-1400) and labetalol in rat isolated
thoracic aorta--do they distinguish between subtypes? Gen Pharmacol. 1992
Sep;23(5):843-5. PubMed PMID: 1358746.

3: Takita M, Kigoshi S, Muramatsu I. Selectivity of bevantolol hydrochloride
towards alpha- and beta-adrenoceptor subtypes in rat cerebral cortex. Jpn J
Pharmacol. 1992 Feb;58(2):193-6. PubMed PMID: 1354761.

4: Kaplan HR. Pharmacology of bevantolol hydrochloride. Am J Cardiol. 1986 Nov
26;58(12):3E-7E. PubMed PMID: 2878599.

5: Kaplan HR. Bevantolol hydrochloride--preclinical pharmacologic profile.
Angiology. 1986 Mar;37(3 Pt 2):254-62. PubMed PMID: 2871786.

6: Löfdahl CG, Svedmyr K, Svedmyr N. Selectivity of bevantolol hydrochloride, a
beta 1-adrenoceptor antagonist, in asthmatic patients. Pharmacotherapy. 1984
Jul-Aug;4(4):205-10. PubMed PMID: 6148733.