WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 600130
Description: 20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. It is therefore one of the most common moulting hormones in insects, crabs, etc. It is also a phytoecdysteroid produced by various plants, including Cyanotis vaga, where its purpose is presumably to disrupt the development and reproduction of insect pests. In arthropods, 20-hydroxyecdysone acts through the ecdysone receptor. Although mammals lack this receptor, 20-hydroxyecdysone may affect mammalian (including human) biological systems in vitro, but there is uncertainty whether any in vivo or physiological effects occur. 20-Hydroxyecdysone is an ingredient of some supplements that aim to enhance physical performance, but there is no clinical evidence for this effect. (Source: http://en.wikipedia.org/wiki/Ecdysterone).
MedKoo Cat#: 600130
Chemical Formula: C27H44O7
Exact Mass: 480.3087
Molecular Weight: 480.63
Elemental Analysis: C, 67.47; H, 9.23; O, 23.30
Synonym: 20Hydroxyecdysone; 20E
IUPAC/Chemical Name: (2b,3b,5b,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
InChi Key: NKDFYOWSKOHCCO-YPVLXUMRSA-N
InChi Code: InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
SMILES Code: CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC([C@]4([H])C[C@@H](O)[C@@H](O)C[C@]4(C)[C@@]3([H])CC[C@]12C)=O
1: CahlÃkovÃ¡ L, MacÃ¡kovÃ¡ K, Chlebek J, Host'Ã¡lkovÃ¡ A, KulhÃ¡nkovÃ¡ A, Opletal L. Ecdysterone and its activity on some degenerative diseases. Nat Prod Commun. 2011 May;6(5):707-18. Review. PubMed PMID: 21615037.