Bergenin
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 600116

CAS#: 477-90-7

Description: Bergenin alias Cuscutin is trihydroxybenzoic acid glycoside. It is the C-glycoside of 4-O-methyl gallic acid. It possesses an O-demethylated derivative called norbergenin. These are chemical compounds and drugs of Ayurveda, commonly known as Paashaanbhed. It shows a potent immunomodulatory effect. Bergenin can be isolated from Bergenia species like Bergenia ciliata and Bergenia ligulata, from rhizomes of Bergenia stracheyi. It is also found in the stem bark of Dryobalanops aromatica, in Ardisia elliptica and in Mallotus japonicus.


Price and Availability

Size
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10mg
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100mg
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1g
USD 300
Size
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25mg
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200mg
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2g
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Size
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50mg
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500mg
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5g
USD 755

Bergenin purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 600116
Name: Bergenin
CAS#: 477-90-7
Chemical Formula: C14H16O9
Exact Mass: 328.07943
Molecular Weight: 328.27
Elemental Analysis: C, 51.22; H, 4.91; O, 43.86


Synonym: Cuscutin

IUPAC/Chemical Name: (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3, 4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one

InChi Key: YWJXCIXBAKGUKZ-HJJNZUOJSA-N

InChi Code: InChI=1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1

SMILES Code: O=C1C2=C(C(O)=C(OC)C(O)=C2)[C@@]3([H])[C@]([C@@H](O)[C@H](O)[C@@H](CO)O3)([H])O1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO.

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Uddin G, Sadat A, Siddiqui BS. Comparative antioxidant and antiplasmodial activities of 11-O-galloylbergenin and bergenin isolated from Bergenia ligulata.   Trop Biomed. 2014 Mar;31(1):143-8. PubMed PMID: 24862054.