ZLN005
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MedKoo CAT#: 510265

CAS#: 49671-76-3

Description: ZLN005 is a PGC-1α Transcriptional Regulator, which shoed some beneficialfEffects on diabetic db/db mice. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice. Hyperglycemia and dyslipidemia also were ameliorated after treatment with ZLN005. Our results demonstrated that a novel small molecule selectively elevated the expression of PGC-1α in myotubes and skeletal muscle and exerted promising therapeutic effects for treating type 2 diabetes.


Price and Availability

Size
Price

10mg
USD 150
1g
USD 1250
Size
Price

100mg
USD 550
2g
USD 1950
Size
Price

500mg
USD 750
5g
USD 3750

ZLN005, purity > 98%, is in stock. Same day shipping after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 510265
Name: ZLN005
CAS#: 49671-76-3
Chemical Formula: C17H18N2
Exact Mass: 250.147
Molecular Weight: 250.33822
Elemental Analysis: C, 81.56; H, 7.25; N, 11.19


Synonym: ZLN005; ZLN-005; ZLN 005.

IUPAC/Chemical Name: 2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazole

InChi Key: LQUNNCQSFFKSSK-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)

SMILES Code: CC(C1=CC=C(C2=NC3=CC=CC=C3N2)C=C1)(C)C


Technical Data

Appearance:
white to off-white solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

  
  
 
 


References

1: Zhang LN, Zhou HY, Fu YY, Li YY, Wu F, Gu M, Wu LY, Xia CM, Dong TC, Li JY, Shen JK, Li J. Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes. 2013 Apr;62(4):1297-307. doi: 10.2337/db12-0703. Epub 2012 Dec 18. PubMed PMID: 23250358; PubMed Central PMCID: PMC3609556.