Gabapentin enacarbil

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 314219

CAS#: 478296-72-9

Description: Gabapentin enacarbil is a prodrug for the anticonvulsant and analgesic drug gabapentin. It was designed for increased oral bioavailability over gabapentin, and human trials showed it to produce extended release of gabapentin with almost twice the overall bioavailability, especially when taken with a fatty meal. Gabapentin enacarbil has passed human clinical trials for the treatment of restless legs syndrome, and initial results have shown it to be well tolerated and reasonably effective. (Source: http://en.wikipedia.org/wiki/Gabapentin_enacarbil).


Price and Availability

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Gabapentin enacarbil is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 314219
Name: Gabapentin enacarbil
CAS#: 478296-72-9
Chemical Formula: C16H27NO6
Exact Mass: 329.18384
Molecular Weight: 329.39
Elemental Analysis: C, 58.34; H, 8.26; N, 4.25; O, 29.14


Synonym: Horizant; Regnite

IUPAC/Chemical Name: (1-{[({(1RS)-1-[isobutyryloxy]ethoxy}carbonyl) amino]methyl}cyclohexyl)acetic acid

InChi Key: TZDUHAJSIBHXDL-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H27NO6/c1-11(2)14(20)22-12(3)23-15(21)17-10-16(9-13(18)19)7-5-4-6-8-16/h11-12H,4-10H2,1-3H3,(H,17,21)(H,18,19)

SMILES Code: O=C(O)CC1(CNC(OC(OC(C(C)C)=O)C)=O)CCCCC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO.

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References