Bethanechol Chloride
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 315283

CAS#: 590-63-6

Description: Bethanechol chloride, a cholinergic agent, is a synthetic esler which is structurally and pharmacologically related to acetylcholine. It is designated chemically as Z-[(aminocarbony) oxy]-N, N, (V-trimethyl-1-propanaminium chloride. Its molecular formula is C7H17CIN202. It is a white, hygroscopic crystalline powder having a slight amine-like odor, freely soluble in water, and has a molecular weight of 196.68. Each tablet for oral administration contains 5 mg, 10 mg, 25 mg or 50 mg bethanechol chloride, USP Tablets also contain the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, (25 mg and 50 mg) D&C~ Yellow # 10 Lake and FD&C Yellow # 6 Lake.


Price and Availability

Size
Price

50mg
USD 50
500mg
USD 120
5g
USD 350
50g
USD 1250
Size
Price

100mg
USD 80
1g
USD 150
10g
USD 550
100g
Ask price
Size
Price

200mg
USD 90
2g
USD 250
25g
USD 950

Bethanechol Chloride purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 315283
Name: Bethanechol Chloride
CAS#: 590-63-6
Chemical Formula: C7H17ClN2O2
Exact Mass: 196.1
Molecular Weight: 196.68
Elemental Analysis: C, 42.75; H, 8.71; Cl, 18.03; N, 14.24; O, 16.27


Synonym:

IUPAC/Chemical Name: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium chloride

InChi Key: XXRMYXBSBOVVBH-UHFFFAOYSA-N

InChi Code: InChI=1S/C7H16N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H-,8,10);1H

SMILES Code: CC(OC(N)=O)C[N+](C)(C)C.[Cl-]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO.

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Suaid HJ, Rocha JN, Martins AC, Cologna AJ, Tucci SJ. Modulation of urethral alpha-sympathetic by parasympathetic before and following bethanechol chloride injection. Int Braz J Urol. 2003 Mar-Apr;29(2):162-5. PubMed PMID: 15745502.

2: Liu L, Rittenhouse AR. Pharmacological discrimination between muscarinic receptor signal transduction cascades with bethanechol chloride. Br J Pharmacol. 2003 Apr;138(7):1259-70. PubMed PMID: 12711626; PubMed Central PMCID: PMC1573771.

3: Allen LV Jr, Erickson MA. Stability of bethanechol chloride, pyrazinamide, quinidine sulfate, rifampin, and tetracycline hydrochloride in extemporaneously compounded oral liquids. Am J Health Syst Pharm. 1998 Sep 1;55(17):1804-9. PubMed PMID: 9775343.

4: Schlatter JL, Saulnier JL. Bethanechol chloride oral solutions: stability and use in infants. Ann Pharmacother. 1997 Mar;31(3):294-6. PubMed PMID: 9066934.

5: Baranowska-Daca E, Torneli J, Popovich RP, Moncrief JW. Use of bethanechol chloride to increase available ultrafiltration in CAPD. Adv Perit Dial. 1995;11:69-72. PubMed PMID: 8534741.

6: Taillandier J, Boiteux JP, Boyer L, Guy L, Giraud B. Re: Detection of missing vesicoureteral reflux with bethanechol chloride-aided voiding cystourethrography. J Urol. 1993 Apr;149(4):867-8. PubMed PMID: 8095993.

7: Araki T, Nakano S, Sugimura Y, Tochigi H, Kawamura J, Kato T, Tajima K, Chigusa I, Saito K, Morisita H, et al. [Efficacy of combination of Ea-0643 (bunazosin hydrochloride) and bethanechol chloride in patients with neurogenic bladder]. Hinyokika Kiyo. 1990 Nov;36(11):1379-83. Japanese. PubMed PMID: 1981126.

8: Harbaugh RE, Reeder TM, Senter HJ, Knopman DS, Baskin DS, Pirozzolo F, Chui HC, Shetter AG, Bakay RA, Leblanc R, et al. Intracerebroventricular bethanechol chloride infusion in Alzheimer's disease. Results of a collaborative double-blind study. J Neurosurg. 1989 Oct;71(4):481-6. PubMed PMID: 2571689.

9: Koyanagi T, Morita H, Gotoh T, Nonomura K, Togashi M, Nantani M. Detection of missing vesicoureteral reflux with bethanechol chloride-aided voiding cystourethrography. J Urol. 1989 Mar;141(3):580-2. PubMed PMID: 2563779.

10: Zgourides GD. Bethanechol chloride as a suggested adjunct to prolonged in vivo exposure therapy in the treatment of paruresis. Percept Mot Skills. 1988 Feb;66(1):319-22. PubMed PMID: 2896331.