Tenovin-1
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406723

CAS#: 380315-80-0

Description: Tenovin-1 is a p53 activator that protects against MDM2-mediated p53 degradation.


Price and Availability

Size
Price

50mg
USD 250
500mg
USD 1450
5g
USD 5650
Size
Price

100mg
USD 450
1g
USD 2450
Size
Price

200mg
USD 750
2g
USD 3850

Tenovin-1 purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406723
Name: Tenovin-1
CAS#: 380315-80-0
Chemical Formula: C20H23N3O2S
Exact Mass: 369.1511
Molecular Weight: 369.48052
Elemental Analysis: C, 65.01; H, 6.27; N, 11.37; O, 8.66; S, 8.68


Synonym: Tenovin1

IUPAC/Chemical Name: N -[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide

InChi Key: WOWJIWFCOPZFGV-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H23N3O2S/c1-13(24)21-16-9-11-17(12-10-16)22-19(26)23-18(25)14-5-7-15(8-6-14)20(2,3)4/h5-12H,1-4H3,(H,21,24)(H2,22,23,25,26)

SMILES Code: O=C(NC(NC1=CC=C(NC(C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>5 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

  
 
 
 


References

1: Lain S, Hollick JJ, Campbell J, Staples OD, Higgins M, Aoubala M, McCarthy A,  Appleyard V, Murray KE, Baker L, Thompson A, Mathers J, Holland SJ, Stark MJ, Pass G, Woods J, Lane DP, Westwood NJ. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.  doi: 10.1016/j.ccr.2008.03.004. PubMed PMID: 18455128; PubMed Central PMCID: PMC2742717.