NU2058
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406329

CAS#: 161058-83-9

Description: NU2058 is a potent CDK inhibitor that has CDK2 IC(50)=17 microM and CDK1 IC(50)=26 microM.


Price and Availability

Size
Price

50mg
USD 190
500mg
USD 1350
Size
Price

100mg
USD 350
1g
USD 2150
Size
Price

200mg
USD 650
2g
USD 3450

NU2058, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406329
Name: NU2058
CAS#: 161058-83-9
Chemical Formula: C12H17N5O
Exact Mass: 247.14331
Molecular Weight: 247.3
Elemental Analysis: C, 58.28; H, 6.93; N, 28.32; O, 6.47


Synonym: NU2058; NU 2058; NU-2058.

IUPAC/Chemical Name: 6-(cyclohexylmethoxy)-9H-purin-2-amine

InChi Key: MWGXGTJJAOZBNW-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)

SMILES Code: NC1=NC(OCC2CCCCC2)=C3N=CNC3=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly.

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

  
 
 
 


References

1: Harrison LR, Ottley CJ, Pearson DG, Roche C, Wedge SR, Dolan ME, Newell DR, Tilby MJ. The kinase inhibitor O6-cyclohexylmethylguanine (NU2058) potentiates the cytotoxicity of cisplatin by mechanisms that are independent of its effect upon CDK2. Biochem Pharmacol. 2009 May 15;77(10):1586-92. doi: 10.1016/j.bcp.2009.02.018. Epub 2009 Mar 5. PubMed PMID: 19426695.