CInQ-03

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406199

CAS#: 500272-80-0

Description: CInQ-03 is a novel and specific MEK inhibitor both in vitro and in vivo.


Price and Availability

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CInQ-03, purity > 98% is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406199
Name: CInQ-03
CAS#: 500272-80-0
Chemical Formula: C22H12ClN5O
Exact Mass: 397.07304
Molecular Weight: 397.82
Elemental Analysis: C, 66.42; H, 3.04; Cl, 8.91; N, 17.60; O, 4.02


Synonym: CInQ03

IUPAC/Chemical Name: 2-chloro-N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)benzamide

InChi Key: HLFGQICCFZTXTP-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H12ClN5O/c23-16-6-2-1-5-14(16)22(29)25-13-9-10-28-19(11-13)15(12-24)20-21(28)27-18-8-4-3-7-17(18)26-20/h1-11H,(H,25,29)

SMILES Code: O=C(NC1=CC2=C(C#N)C3=NC4=CC=CC=C4N=C3N2C=C1)C5=CC=CC=C5Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>5 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

  
 
 
 


References

 1: Kim DJ, Lee MH, Reddy K, Li Y, Lim DY, Xie H, Lee SY, Yeom YI, Bode AM, Dong Z. CInQ-03, a novel allosteric MEK inhibitor, suppresses cancer growth in vitro and in vivo. Carcinogenesis. 2013 Feb 14. [Epub ahead of print] PubMed PMID: 23354306.