CAY10505
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406316

CAS#: 1218777-13-9

Description: CAY10505 is a phosphatidylinositol 3-kinase-γ inhibitor , was found to significantly improve acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats. CAY10505 , may improve hypertension-associated vascular endothelial dysfunction. Inhibition of PI3Kγ might be a useful approach in the therapeutics of vascular endothelium dysfunction.


Price and Availability

Size
Price

10mg
USD 230
Size
Price

50mg
USD 530
Size
Price

CAY10505 purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406316
Name: CAY10505
CAS#: 1218777-13-9
Chemical Formula: C14H8FNO3S
Exact Mass: 289.02089
Molecular Weight: 289.28
Elemental Analysis: C, 58.13; H, 2.79; F, 6.57; N, 4.84; O, 16.59; S, 11.08


Synonym: CAY10505; CAY 10505; CAY10505

IUPAC/Chemical Name: (E)-5-((5-(4-fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione

InChi Key: UFBTYTGRUBUUIL-KPKJPENVSA-N

InChi Code: InChI=1S/C14H8FNO3S/c15-9-3-1-8(2-4-9)11-6-5-10(19-11)7-12-13(17)16-14(18)20-12/h1-7H,(H,16,17,18)/b12-7+

SMILES Code: O=C(NC/1=O)SC1=C\C2=CC=C(C3=CC=C(F)C=C3)O2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not soluble in water or ethanol.

Shelf Life:
>2 years if stored properly.

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

  
 
 
 


References

1: Tyagi S, Sharma S, Budhiraja RD. Effect of phosphatidylinositol 3-kinase-γ inhibitor CAY10505 in hypertension, and its associated vascular endothelium dysfunction in rats. Can J Physiol Pharmacol. 2012 Jul;90(7):881-5. doi: 10.1139/y2012-089. Epub 2012 Jun 25. PubMed PMID: 22731503.