T900607

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 205996

CAS#: 261944-52-9

Description: T900607 is a pentafluorophenylsulfonamide compound with potential antineoplastic activity. T900607 inhibits tubulin polymerization by binding irreversibly to colchicine binding sites, resulting in cell cycle arrest and apoptosis.


Price and Availability

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T900607 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 205996
Name: T900607
CAS#: 261944-52-9
Chemical Formula: C14H10F5N3O4S
Exact Mass: 411.03122
Molecular Weight: 411.3
Elemental Analysis: C, 40.88; H, 2.45; F, 23.10; N, 10.22; O, 15.56; S, 7.80


Synonym: T900607, T-900607, T 900607, T607; T-607, T 607

IUPAC/Chemical Name: N-(4-Methoxy-3-ureidophenyl)-2,3,4,5,6-pentafluorobenzenesulfonamide

InChi Key: FSXLOWIFSZNIMV-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H10F5N3O4S/c1-26-7-3-2-5(4-6(7)21-14(20)23)22-27(24,25)13-11(18)9(16)8(15)10(17)12(13)19/h2-4,22H,1H3,(H3,20,21,23)

SMILES Code: O=S(C1=C(F)C(F)=C(F)C(F)=C1F)(NC2=CC=C(OC)C(NC(N)=O)=C2)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>5 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

 1: Gelmon KA, Belanger K, Soulieres D, Britten C, Chia S, Charpentier D, Chi K, Powers J, Walsh W, Seymour L. A phase I study of T900607 given once every 3 weeks in patients with advanced refractory cancers; National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG) IND 130. Invest New Drugs. 2005 Oct;23(5):445-53. PubMed PMID: 16133796.