WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 525715
Description: Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. Molidustat is currently clinical trials at Bayer for the treatment of patients suffering from renal anemia due to chronic kidney disease.
MedKoo Cat#: 525715
Chemical Formula: C13H14N8O2
Exact Mass: 314.12397
Molecular Weight: 314.3
Elemental Analysis: C, 49.68; H, 4.49; N, 35.65; O, 10.18
Synonym: BAY 853934; BAY-853934; BAY853934; Molidustat.
IUPAC/Chemical Name: 2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one
InChi Key: IJMBOKOTALXLKS-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2
SMILES Code: O=C1N(C2=NC=NC(N3CCOCC3)=C2)NC=C1N4N=NC=C4