PK-10 | synergistic antibacterial agent | Fluconazole

PK-10
new

featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 125222

CAS#: N/A

Description: PK-10 is a synergistic antibacterial agent of Fluconazole.

Chemical Structure

PK-10

CAS# N/A

Instruction

Theoretical Analysis

MedKoo Cat#: 125222
Name: PK-10
CAS#: N/A
Chemical Formula: C35H36F3N5O
Exact Mass: 599.29
Molecular Weight: 599.700
Elemental Analysis: C, 70.10; H, 6.05; F, 9.50; N, 11.68; O, 2.67

Price and Availability

Size	Price	Availability
100mg	USD 750	2 Weeks
200mg	USD 1250	2 Weeks
500mg	USD 2650	2 Weeks
1g	USD 3850	2 Weeks
2g	USD 5950	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: PK-10; PK10; PK 10

IUPAC/Chemical Name: (E)-3-(2-(4-methylpiperazin-1-yl)quinolin-3-yl)-1-(4-(4-(4-(trifluoromethyl)benzyl)piperazin-1-yl)phenyl)prop-2-en-1-one

InChi Key: SINLLFFCVCSBBD-XNTDXEJSSA-N

InChi Code: InChI=1S/C35H36F3N5O/c1-40-16-20-43(21-17-40)34-29(24-28-4-2-3-5-32(28)39-34)10-15-33(44)27-8-13-31(14-9-27)42-22-18-41(19-23-42)25-26-6-11-30(12-7-26)35(36,37)38/h2-15,24H,16-23,25H2,1H3/b15-10+

SMILES Code: O=C(C1=CC=C(N2CCN(CC2)CC3=CC=C(C(F)(F)F)C=C3)C=C1)/C=C/C4=CC5=C(N=C4N6CCN(CC6)C)C=CC=C5

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 599.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Blahos J 2nd, Whalin ME, Krueger KE. Identification and purification of a
10-kilodalton protein associated with mitochondrial benzodiazepine receptors. J
Biol Chem. 1995 Sep 1;270(35):20285-91. doi: 10.1074/jbc.270.35.20285. PMID:
7657598.

2: Dickson LB, Campbell CL, Juneja P, Jiggins FM, Sylla M, Black WC 4th. Exon-
Enriched Libraries Reveal Large Genic Differences Between Aedes aegypti
from Senegal, West Africa, and Populations Outside Africa. G3 (Bethesda). 2017
Feb 9;7(2):571-582. doi: 10.1534/g3.116.036053. PMID: 28007834; PMCID:
PMC5295602.

3: Campbell CL, Dickson LB, Lozano-Fuentes S, Juneja P, Jiggins FM, Black WC
4th. Alternative patterns of sex chromosome differentiation in Aedes aegypti
(L). BMC Genomics. 2017 Dec 4;18(1):943. doi: 10.1186/s12864-017-4348-4. PMID:
29202694; PMCID: PMC5716240.

4: Olé Sangba ML, Sidick A, Govoetchan R, Dide-Agossou C, Ossè RA, Akogbeto M,
Ndiath MO. Evidence of multiple insecticide resistance mechanisms in Anopheles
gambiae populations in Bangui, Central African Republic. Parasit Vectors. 2017
Jan 13;10(1):23. doi: 10.1186/s13071-016-1965-8. PMID: 28086840; PMCID:
PMC5237250.

Your view history

PK-10 new featured