GSK1059615
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 205739

CAS#: 958852-01-1

Description: GSK1059615 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor GSK1059615 inhibits PI3K in the PI3K/AKT kinase signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane and an increase in mitochondrial membrane permeability, followed by apoptosis. Bax is a member of the proapoptotic Bcl-2 family of proteins. PIK3, an enzyme often overexpressed in cancer cells, plays a crucial role in tumor cell regulation and survival. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).


Price and Availability

Size
Price

5mg
USD 120
50mg
USD 450
500mg
USD 1650
5g
USD 6950
50g
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Size
Price

10mg
USD 150
100mg
USD 650
1g
USD 2650
10g
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100g
Ask price
Size
Price

25mg
USD 250
200mg
USD 950
2g
USD 3950
20g
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GSK1059615, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 205739
Name: GSK1059615
CAS#: 958852-01-1
Chemical Formula: C18H11N3O2S
Exact Mass: 333.0572
Molecular Weight: 333.36384
Elemental Analysis: C, 64.85; H, 3.33; N, 12.60; O, 9.60; S, 9.62


Synonym: GSK1059615; GSK-1059615; GSK-1059615.

IUPAC/Chemical Name: (E)-4-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,5-dione

InChi Key: SSROGLWTGKZPRA-MHWRWJLKSA-N

InChi Code: InChI=1S/C18H11N3O2S/c22-17-16(21-18(23)24-17)10-11-1-2-15-14(9-11)13(5-8-20-15)12-3-6-19-7-4-12/h1-10H,(H,21,23)/b16-10+

SMILES Code: O=C(N/C1=C/C2=CC=C3N=CC=C(C4=CC=NC=C4)C3=C2)SC1=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

 
 
 
 


References