RG7304

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 205612

CAS#: 213406-50-9

Description: RG7304, also known as R7304 or CK-127, is a MEK inhibitor currently in clinical trials.


Price and Availability

Size
Price

10mg
Not available
100mg
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1g
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Size
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25mg
Not available
200mg
Not available
2g
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Size
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50mg
Not available
500mg
Not available
5g
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RG7304 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 205612
Name: RG7304
CAS#: 213406-50-9
Chemical Formula: C12H12N4O
Exact Mass: 228.1011
Molecular Weight: 228.255
Elemental Analysis: C, 63.15; H, 5.30; N, 24.55; O, 7.01


Synonym: CKI27; CK127; CK 127; RG7304; RG7304; RG 7304 R7304.

IUPAC/Chemical Name: (E)-5-(2-benzylidene-1-methylhydrazinyl)pyridazin-3(2H)-one

SMILES Code: CN(C(C=NN1)=CC1=O)/N=C/C2=CC=CC=C2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

CKI 27 (RG7304) is a MEK inhibitor currently in clinical trials.
 
 
 


References

 1: Chiou GC, Xuan B, Yamasaki T, Okawara T. Anti-inflammation and
antifibroblastic actions of interleukin-1 blockers. J Ocul Pharmacol Ther. 1998
Aug;14(4):375-88. PubMed PMID: 9715441.