Cinnamate-GW9662-16

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MedKoo CAT#: 130166

CAS#: N/A

Description: Cinnamate-GW9662-16 is a covalent PPARγ agonist.


Chemical Structure

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Cinnamate-GW9662-16
CAS# N/A

Theoretical Analysis

MedKoo Cat#: 130166
Name: Cinnamate-GW9662-16
CAS#: N/A
Chemical Formula: C26H23ClN2O6
Exact Mass: 494.12
Molecular Weight: 494.930
Elemental Analysis: C, 63.10; H, 4.68; Cl, 7.16; N, 5.66; O, 19.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Cinnamate-GW9662-16; Cinnamate GW9662-16; Cinnamate GW9662 16; Cinnamate-GW9662 16

IUPAC/Chemical Name: ethyl (E)-3-(4-(3-(2-chloro-5-nitrobenzamido)phenethoxy)phenyl)acrylate

InChi Key: DEEALLFMKVTXOT-MDWZMJQESA-N

InChi Code: InChI=1S/C26H23ClN2O6/c1-2-34-25(30)13-8-18-6-10-22(11-7-18)35-15-14-19-4-3-5-20(16-19)28-26(31)23-17-21(29(32)33)9-12-24(23)27/h3-13,16-17H,2,14-15H2,1H3,(H,28,31)/b13-8+

SMILES Code: O=C(OCC)/C=C/C1=CC=C(OCCC2=CC=CC(NC(C3=CC([N+]([O-])=O)=CC=C3Cl)=O)=C2)C=C1

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 494.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Utsugi Y, Kobuchi H, Kawamura Y, Atito ASA, Nagao M, Isoda H, Miyamae Y. Importance of the Proximity and Orientation of Ligand-Linkage to the Design of Cinnamate-GW9662 Hybrid Compounds as Covalent PPARγ Agonists. Molecules. 2019 May 27;24(10):2019. doi: 10.3390/molecules24102019. PMID: 31137814; PMCID: PMC6571965.