HM41322

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 130085

CAS#: N/A

Description: HM41322 is a SGLT1/2 dual inhibitor and was shown to maximize the amount of glucose excreted through the urine. HM41322 shows promise as an agent for postprandial glucose control.

Chemical Structure

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HM41322
CAS# N/A
Instruction

Theoretical Analysis

MedKoo Cat#: 130085
Name: HM41322
CAS#: N/A
Chemical Formula: C24H30O5
Exact Mass: 398.21
Molecular Weight: 398.500
Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 72.34; H, 7.59; O, 20.07

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: HM41322

IUPAC/Chemical Name: (2S,3R,4R,5S,6R)-2-[7-(4-Ethylbenzyl)-2,3-dihydro-1H-inden-5-yl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

InChi Key: OVFHLFVDLPPVNL-SJSRKZJXSA-N

InChi Code: InChI=1S/C24H30O5/c1-2-14-6-8-15(9-7-14)10-17-12-18(11-16-4-3-5-19(16)17)24-23(28)22(27)21(26)20(13-25)29-24/h6-9,11-12,20-28H,2-5,10,13H2,1H3/t20-,21-,22+,23-,24+/m1/s1

SMILES Code: O[C@H]1[C@H](C2=CC3=C(CCC3)C(CC4=CC=C(CC)C=C4)=C2)O[C@H](CO)[C@@H](O)[C@@H]1O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 398.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Lee KH, Lee SD, Kim N, Suh KH, Kim YH, Sim SS. Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo. Korean J Physiol Pharmacol. 2019 Jan;23(1):55-62. doi: 10.4196/kjpp.2019.23.1.55. Epub 2018 Dec 26. PMID: 30627010; PMCID: PMC6315097.