Propargyl-PEG4-Sulfone-PEG4-t-butyl ester
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MedKoo CAT#: 122033

CAS#: 2055024-43-4

Description: Propargyl-PEG4-Sulfone-PEG4-t-butyl ester is a PEG linker containing a propargyl group and t-butyl protected carboxyl group acid. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The t-butyl protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. The protected acid can be deprotected by acidic or basic hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.

Chemical Structure

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Propargyl-PEG4-Sulfone-PEG4-t-butyl ester
CAS# 2055024-43-4
Instruction

Theoretical Analysis

MedKoo Cat#: 122033
Name: Propargyl-PEG4-Sulfone-PEG4-t-butyl ester
CAS#: 2055024-43-4
Chemical Formula: C26H48O12S
Exact Mass: 584.29
Molecular Weight: 584.720
Elemental Analysis: C, 53.41; H, 8.27; O, 32.83; S, 5.48

Price and Availability

Size Price Availability Quantity
100mg USD 600 2 Weeks
250mg USD 950 2 Weeks
500mg USD 1400 2 Weeks
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Synonym: Propargyl PEG4 Sulfone PEG4 t butyl ester, PEG4-t-butyl ester, Propargyl-PEG4-Sulfone

IUPAC/Chemical Name: tert-butyl 16,16-di(l1-oxidanyl)-4,7,10,13,19,22,25,28-octaoxa-16l4-thiahentriacont-30-ynoate

InChi Key: CWRIXFFIEVWNLO-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H48O12S/c1-5-7-30-9-11-32-13-15-34-17-19-36-21-23-39(28,29)24-22-37-20-18-35-16-14-33-12-10-31-8-6-25(27)38-26(2,3)4/h1H,6-24H2,2-4H3

SMILES Code: [O]S(CCOCCOCCOCCOCCC(OC(C)(C)C)=O)([O])CCOCCOCCOCCOCC#C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 584.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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