PM 170

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 208540

CAS#: 80842-08-6

Description: PM 170 is a new anorectic drug

Chemical Structure

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PM 170
CAS# 80842-08-6
Instruction

Theoretical Analysis

MedKoo Cat#: 208540
Name: PM 170
CAS#: 80842-08-6
Chemical Formula: C15H21Cl2NO3
Exact Mass: 333.09
Molecular Weight: 334.237
Elemental Analysis: C, 53.90; H, 6.33; Cl, 21.21; N, 4.19; O, 14.36

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: PM 170, 3-Piperidinemethanol, 1-methyl-, (p-chlorophenoxy)acetate, hydrochloride, EINECS 279-575-7

IUPAC/Chemical Name: 3-((2-(4-chlorophenoxy)acetoxy)methyl)-1-methylpiperidin-1-ium chloride

InChi Key: JHJOZTMFSDMYCE-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H20ClNO3.ClH/c1-17-8-2-3-12(9-17)10-20-15(18)11-19-14-6-4-13(16)5-7-14;/h4-7,12H,2-3,8-11H2,1H3;1H

SMILES Code: C[NH+]1CCCC(C1)COC(COc2ccc(Cl)cc2)=O.[Cl-]

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 334.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Massicot F, Falcou R, Heymans F, Godfroid JJ, Apfelbaum M. Effects of a new anorectic drug (PM 170) on development of gold thioglucose-induced obesity in mice. Gen Pharmacol. 1987;18(3):249-52. doi: 10.1016/0306-3623(87)90007-3. PMID: 3106136.


2: Sadler AWE, Hogan L, Fraser B, Rendina LM. Cutting edge rare earth radiometals: prospects for cancer theranostics. EJNMMI Radiopharm Chem. 2022 Aug 26;7(1):21. doi: 10.1186/s41181-022-00173-0. PMID: 36018527; PMCID: PMC9418400.


3: Thomas M. Idées actuelles sur le traitement de l'obésité [Current ideas on the treatment of obesity]. Rev Med Interne. 1986 May;7(3):329-33. French. doi: 10.1016/s0248-8663(86)80018-2. PMID: 2429355.


4: Massicot F, Ricquier D, Godfroid JJ, Apfelbaum M. Activation of energy expenditure in the rat by a new non-amphetaminic compound: the (4-chlorophenoxyacetate) N-methyl 3-hydroxymethyl piperidine, hydrochloride (PM 170). Int J Obes. 1985;9(6):451-8. PMID: 3841663.


5: van der Ham M, Albersen M, de Koning TJ, Visser G, Middendorp A, Bosma M, Verhoeven-Duif NM, de Sain-van der Velden MG. Quantification of vitamin B6 vitamers in human cerebrospinal fluid by ultra performance liquid chromatography-tandem mass spectrometry. Anal Chim Acta. 2012 Jan 27;712:108-14. doi: 10.1016/j.aca.2011.11.018. Epub 2011 Nov 18. PMID: 22177072.


6: Massicot F, Arapis G, Falcou R, Apfelbaum M, Godfroid JJ. Activités anti- obésités du chlorhydrate de chloro-4 phénoxyacétate de N-méthyl hydroxyméthyl-3 pipéridine chez des souris traitées par l'aurothioglucose [Anti-obesity activity of 3-hydroxymethyl N-methyl piperidine 4-chlorophenoxyacetate hydrochloride in mice treated with gold thioglucose]. C R Acad Sci III. 1986;303(17):703-8. French. PMID: 3101985.