BCN-NHS
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 121148

CAS#: 1516551-46-4

Description: BCN-NHS, also known as BCN-succinimidyl ester, is a ProTAC building block. BCN-NHS may be used to functionalize the primary amines of the lysine residue of recombinant elastin-like proteins (ELPs). It may also be used to synthesize bicyclononyne functionalized poly(ethylene glycol) polymer coatings with anti-fouling properties towards protein adhesion and cell adhesion for supramolecular ureidopyrimidinone (UPy) based materials.

Chemical Structure

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BCN-NHS
CAS# 1516551-46-4
Instruction

Theoretical Analysis

MedKoo Cat#: 121148
Name: BCN-NHS
CAS#: 1516551-46-4
Chemical Formula: C15H17NO5
Exact Mass: 291.11
Molecular Weight: 291.300
Elemental Analysis: C, 61.85; H, 5.88; N, 4.81; O, 27.46

Price and Availability

Size Price Availability Quantity
10mg USD 380 2 Weeks
100mg USD 970 2 Weeks
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Synonym: BCN-succinimidyl ester

IUPAC/Chemical Name: (1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-succinimidyl carbonate

InChi Key: SKTDJYHCSCYLQU-ZSBIGDGJSA-N

InChi Code: 1S/C15H17NO5/c17-13-7-8-14(18)16(13)21-15(19)20-9-12-10-5-3-1-2-4-6-11(10)12/h10-12H,3-9H2/t10-,11+,12-

SMILES Code: [H][C@@]12CCC#CCC[C@]1([H])[C@@H]2COC(ON3C(CCC3=O)=O)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 291.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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