ITD-1
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 510341

CAS#: 1099644-42-4

Description: ITD-1 is a selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways. ITD-1 selectively enhanced the differentiation of uncommitted mesoderm to cardiomyocytes, but not to vascular smooth muscle and endothelial cells. ITD-1 is a highly selective TGF-β inhibitor and reveals an unexpected role for TGF-β signaling in controlling cardiomyocyte differentiation from multipotent cardiovascular precursors.


Price and Availability

Size
Price

10mg
USD 150
100mg
USD 650
1g
USD 2650
Size
Price

25mg
USD 250
200mg
USD 950
2g
USD 3950
Size
Price

50mg
USD 450
500mg
USD 1650
5g
USD 5850

ITD-1, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 510341
Name: ITD-1
CAS#: 1099644-42-4
Chemical Formula: C27H29NO3
Exact Mass: 415.21474
Molecular Weight: 415.52
Elemental Analysis: C, 78.04; H, 7.03; N, 3.37; O, 11.55


Synonym: ITD1; ITD 1; ITD-1.

IUPAC/Chemical Name: ethyl 4-([1,1'-biphenyl]-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

InChi Key: ULFUJLFTRWWLPO-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3,4)16-22(29)25(21)24(23)20-13-11-19(12-14-20)18-9-7-6-8-10-18/h6-14,24,28H,5,15-16H2,1-4H3

SMILES Code: O=C(C1=C(C)NC2=C(C(CC(C)(C)C2)=O)C1C3=CC=C(C4=CC=CC=C4)C=C3)OCC


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

  
 
 
 


References