AZD9496
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206208

CAS#: 1639042-08-2 (free base)

Description: AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer.


Price and Availability

Size
Price

10mg
USD 190
100mg
USD 850
1g
USD 3650
Size
Price

25mg
USD 350
200mg
USD 1450
2g
USD 5950
Size
Price

50mg
USD 550
500mg
USD 2450
5g
Ask price

AZD9496, purity > 98%, is in stock. The same day shipping out after order is received. Note: the estimated shipping out time for order > 2g may be 2 weeks.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 206208
Name: AZD9496
CAS#: 1639042-08-2 (free base)
Chemical Formula: C25H25F3N2O2
Exact Mass: 442.18681
Molecular Weight: 442.48
Elemental Analysis: C, 67.86; H, 5.70; F, 12.88; N, 6.33; O, 7.23


Related CAS #: 1639042-08-2 (free base)   1639042-28-6 (maleate)    

Synonym: AZD9496; AZD-9496; AZD 9496.

IUPAC/Chemical Name: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid

InChi Key: DFBDRVGWBHBJNR-BBNFHIFMSA-N

InChi Code: InChI=1S/C25H25F3N2O2/c1-14-10-17-16-6-4-5-7-20(16)29-23(17)24(30(14)13-25(2,3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9,11-12,14,24,29H,10,13H2,1-3H3,(H,31,32)/b9-8+/t14-,24-/m1/s1

SMILES Code: O=C(O)/C=C/C1=CC(F)=C([C@H]2N(CC(C)(F)C)[C@H](C)CC3=C2NC4=C3C=CC=C4)C(F)=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

 Related CAS#
CAS#1639042-08-2 ( AZD9496 free base)
CAS#1639042-28-6 ( AZD9496 maleate). 
 
 
 


References